2018
DOI: 10.1016/j.artd.2018.02.014
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What are the incidence and risk factors of in-hospital mortality after venous thromboembolism events in total hip and knee arthroplasty patients?

Abstract: BackgroundPulmonary embolism and deep vein thrombosis, together referred to as venous thromboembolism (VTE), are serious and potentially preventable complications after total hip arthroplasty and total knee arthroplasty. The aim of this study was to investigate the incidence of mortality after VTE events and assess the risk factors that are associated with it.MethodsThe Nationwide Inpatient Sample was used to estimate the total number of total hip arthroplasty, total knee arthroplasty, VTE events, and mortalit… Show more

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Cited by 60 publications
(43 citation statements)
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“…Subgroup analysis according to index diagnoses may garner a more detailed analysis of results. Additionally, several risk factors for DVT were not available for analysis including a history of DVT/PE, family history of thrombosis, positive Factor V Leiden or other hereditary coagulopathies, blood type, bilateral procedures, and recent stroke [5,6,9,10,12]. The NSQIP database does not provide information regarding the type of VTE prophylaxis or treatment/rehabilitation protocols, which may play a role in the reduction of VTE.…”
Section: Discussionmentioning
confidence: 99%
“…Subgroup analysis according to index diagnoses may garner a more detailed analysis of results. Additionally, several risk factors for DVT were not available for analysis including a history of DVT/PE, family history of thrombosis, positive Factor V Leiden or other hereditary coagulopathies, blood type, bilateral procedures, and recent stroke [5,6,9,10,12]. The NSQIP database does not provide information regarding the type of VTE prophylaxis or treatment/rehabilitation protocols, which may play a role in the reduction of VTE.…”
Section: Discussionmentioning
confidence: 99%
“…The 80 years and over age group and the presence of comorbidities were the main variables that were independently associated with higher mortality, which is consistent with reports by other studies. [24][25][26][27][28] In addition, sociodemographic factors, such as age group and region, related to the patients were also associated with mortality. The patient's insurer was found to be an independent predictor of mortality.…”
Section: Discussionmentioning
confidence: 99%
“…Various predisposing factors play a role in the development of venous thromboembolism (VTE; Tables and ) . One possibility in our case is that the PE could have occurred as a result of undiagnosed existing DVT of the deep pelvic veins, as the patient had been immobilized in a wheelchair for a few years.…”
Section: Discussionmentioning
confidence: 92%
“…Venous thromboembolism events are a serious and potentially fatal complication that should be avoided by sufficient preoperative, perioperative, and post‐operative prophylaxis. Therefore, we recommend that all patients undergoing the Endo‐Exo‐Prosthesis surgery should be assessed using a preoperative questionnaire to categorize the risk of VTE ( Table ) . Moreover, if their risk profile is increased, assessment should be followed by a preoperative Doppler ultrasound of the lower limbs, MR imaging of the pelvis, and perioperative antithrombotic prophylaxis according to the guidelines of the German Association of the Scientific Medical Societies of Thromboembolism.…”
Section: Discussionmentioning
confidence: 99%