What are the non-cardiac prognostic factors affecting mortality in neonates with aortopulmonary shunt

Özlü, Ferda; Erdem, Sevcan; Göçen, Uğur; Demir, Fadli; Atalay, Atakan; Akçalı, Mustafa; Özbarlas, Nazan; Satar, Mehmet

doi:10.1080/14767058.2019.1609928

Cited by 2 publications

(2 citation statements)

References 26 publications

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“…Mean systolic blood pressure was evaluated according to gestational age nomograms and was accepted as normal if systolic blood pressure was 55 to 75 mm Hg and diastolic blood pressure was 40 to 45 mm Hg. 16 After operation, dopamine 5 to 15 µg/kg/min, adrenalin infusion 0.03 to 0.2 µg/kg/min, milrinone 0.5 to 0.8 µg/kg/min were started if needed. If hypotension continued, noradrenalin at a dose of 0.03 to 0.1 µg/kg/min with/without 0.5 g/kg daily dexamethasone as maintenance therapy after 0.5 g/kg loading was administered.…”

Section: Methodsmentioning

confidence: 99%

Ischemic-Modified Albumin in Neonates with Congenital Heart Defects

et al. 2022

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Objectives Ischemia-modified albumin (IMA) is a new biochemical marker of ischemia. We aimed to search blood IMA levels in neonates with congenital heart defects. Study Design During the study period, patients diagnosed with congenital heart disease and newborns with a diagnosis of hyperbilirubinemia as a control group were included in the study. IMA level was analyzed using the IMA absorbance unit (ABSU) method. Results In total, 57 newborns with congenital heart disease requiring cardiac operation for the study group and 38 newborns for the control group were included. There was no difference between the two groups in terms of gender, mode of delivery, and weeks of gestation. The average IMA values in the control group were 0.19 ± 0.09 ABSU. The prepostoperative mean IMA values of the patient group were 0.22 ± 0.07 and 0.23 ± 0.07 ABSU, respectively. Comparison of the postoperative IMA with the mean of the control group was statistically significant. Preoperative and postoperative IMA values of patients who have died due to primary heart disease and surgical complications were 0.21 ± 0.07 (0.08–0.32) ABSU and 0.25 ± 0.06 (0.12–0.36) ABSU, respectively. IMA levels were not statistically different between the two groups. Conclusion Hypoxia and ischemia in congenital heart disease in the newborn period both preoperatively and postoperatively were important in prognosis. IMA was higher in the postoperative group. Many comprehensive studies are important in terms of preventing complications and decreasing mortality and morbidity by commenting on prognosis. Key Points

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Section: Methodsmentioning

confidence: 99%

Ischemic-Modified Albumin in Neonates with Congenital Heart Defects

et al. 2022

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“…With the steady improvement of the comprehensive strength in medicine, congenital heart disease continues to develop in a small, difficult, and in-depth direction while operative indications continue to expand and many forbidden zones have been constantly examined in terms of systemic-pulmonary shunt [1][2][3][4][5][6][7]. The number of children that undergo one or more systemicpulmonary shunt is increasing, however, there are few reports on the second systemic pulmonary shunt.…”

Section: Introductionmentioning

confidence: 99%

A summary of second systemic pulmonary shunt for congenital heart disease with pulmonary hypoxemia

Yang

Jing

Chen

et al. 2020

J Cardiothorac Surg

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Background There has been an increasing number of children with congenital heart disease that undergo primary or second systemic-pulmonary shunt, while there are few reports on the second systemic-pulmonary shunt. Therefore, this study summarizes the experience of second systemic-pulmonary shunt for congenital heart disease in our hospital. Methods and results Sixty-five children with congenital heart disease who underwent systemic-pulmonary shunt for the second time in our hospital were analyzed. At the early stage after the operation, cyanosis improved and SpO2 significantly increased. One patient died in hospital (1.54%) and the causes of death were aggravated atrioventricular regurgitation, low cardiac output syndrome, and liver failure. Early complications occurred in 18 patients (27.7%). All the children were rechecked in our hospital every 3–6 months and the McGoon index significantly increased. Conclusion Systemic-pulmonary artery shunt can promote pulmonary vascular development, improve cyanosis symptoms, and increase the chance of radical treatment in children with pulmonary vascular dysplasia.

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What are the non-cardiac prognostic factors affecting mortality in neonates with aortopulmonary shunt

Cited by 2 publications

References 26 publications

Ischemic-Modified Albumin in Neonates with Congenital Heart Defects

Ischemic-Modified Albumin in Neonates with Congenital Heart Defects

A summary of second systemic pulmonary shunt for congenital heart disease with pulmonary hypoxemia

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