What brings adults with Down syndrome to the hospital? A retrospective review of a Spanish cohort between 1997 and 2014

Abstract

Objectives: To describe the clinical and epidemiological characteristics of adult patients with Down syndrome admitted to Spanish hospitals between 1997 and 2014. Secondary goals were to study trend changes over time, and to analyse differences between patients admitted to medical and surgical departments. Patients and Methods: Retrospective observational study on data collected from the Minimum Basic Dataset (MBDS, Conjunto Mínimo Básico de Datos [CMBD]) of admissions of adults with Down syndrome to hospitals belonging to the Spanish

A French nationwide study compared various conditions and healthcare use of individuals < 65 years with a Down’s syndrome to those without

“…We report here that IDS, particularly the youngest, were more frequently admitted to hospital, particularly those with cardiac diseases 21 , 23 . The frequency of diagnoses differed between the ISD and NSD.…”

Down’s syndrome (DS) in France: a nationwide observational study on prevalence &lt;65 years, mortality, comorbidities, and healthcare use in 2019 relative to non-DS individuals

“…We report here that individuals with DS, particularly the youngest, were more frequently admitted to hospital, particularly those with cardiac diseases [21,23]. The frequency of diagnoses differed between the populations of people with and without DS.…”

“…There is a need to improve the treatment of aging-related disorders or diseases with an earlier onset in the context of DS, such as Alzheimer's disease, with an adaptation of transitions in healthcare [16][17][18][19][20][21].The prevalence of common disease conditions and causes of death have mostly been reported for speci c conditions and in a few recent large cohorts of individuals with DS or population studies not taking healthcare use into account [14,[20][21][22]. Hospital diagnoses over the individual's lifespan are also frequently not detailed for chronic and acute diagnoses [22][23][24]. Moreover, comparisons of the annual use of various healthcare services by individuals have rarely been reported for national populations.…”

Analysis of the circumstances associated with death and predictors of mortality in Spanish adults with Down syndrome, 1997–2014

“…We performed a retrospective observational study using data retrieved from the Minimum Basic Dataset (MBDS, Conjunto Mínimo Básico de Datos [CMBD]) of all adult patients discharged from any hospital department in the Spanish National Health System between 1997and 2014. More recent data (2015 were not available from the Ministry of Health at the beginning of the study.…”

“…Only emergency admissions were included in the analysis, that is, those channelled through the emergency department (compared to scheduled hospital admissions). Recent works have shown a significant difference among these two populations; the first corresponding mainly to medical admissions of older, more fragile adults with DS and the latter, to scheduled surgical admissions of younger adults (Aparicio et al, 2022), the former being our population of interest. Deceased patients were identified through the administrative variable "destination after discharge", by selecting the outcome "exitus", or death.…”