Current estimates of the normalized accretion rates of quasars (L/L Edd ), rely on measuring the velocity widths of broad optical-UV emission lines (e.g., Hβ and Mg II λ 2800). However, such lines tend to be weak or inaccessible in the most distant quasars, leading to increasing uncertainty in L/L Edd estimates at z > 6. Utilizing a carefully selected sample of 53 radio-quiet quasars that have Hβ and C IV λ 1549 spectroscopy as well as Chandra coverage, we searched for a robust accretion-rate indicator for quasars, particularly at the highest-accessible redshifts (z ∼ 6 − 7). Our analysis explored relationships between the Hβ -based L/L Edd , the equivalent width (EW) of C IV, and the optical-to-X-ray spectral slope (α ox ). Our results show that EW(C IV) is the strongest indicator of the Hβ -based L/L Edd parameter, consistent with previous studies, although significant scatter persists particularly for sources with weak C IV lines. We do not find evidence for the α ox parameter improving this relation, and we do not find a significant correlation between α ox and Hβ -based L/L Edd . This absence of an improved relationship may reveal a limitation in our sample. X-ray observations of additional luminous sources, found at z 1, may allow us to mitigate the biases inherent in our archival sample and test whether X-ray data could improve L/L Edd estimates. Furthermore, deeper X-ray observations of our sources may provide accurate measurements of the hard-X-ray power-law photon index (Γ), which is considered an unbiased L/L Edd indicator. Correlations between EW(C IV) and α ox with Γ-based L/L Edd may yield a more robust prediction of a quasar normalized accretion rate.