What does quality of life refer to in bipolar disorders research? A systematic review of the construct's definition, usage and measurement

Morton, Emma; Michalak, Erin E.; Murray, Greg

doi:10.1016/j.jad.2017.01.026

Cited by 47 publications

(32 citation statements)

References 63 publications

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“…Subjective assessments and patient-reported outcomes are gaining ground in the field of BD (Morton et al, 2017; Bonnín et al, 2018b). As in psychosocial functioning, the problem with subjective measures is the variability in the definitions and in the instruments to assess the subjective experience of these patients (Morton et al, 2017). It is common that terms such as QoL, well-being or life satisfaction are used as synonyms and interchangeable terms (Morton et al, 2017).…”

Section: Personal Recovery: Well-being and Qolmentioning

confidence: 99%

“…As in psychosocial functioning, the problem with subjective measures is the variability in the definitions and in the instruments to assess the subjective experience of these patients (Morton et al, 2017). It is common that terms such as QoL, well-being or life satisfaction are used as synonyms and interchangeable terms (Morton et al, 2017). Moreover, the current lack of consensus between these construct definitions add uncertainty and complication to select an appropriate instrument to measure this dimension.…”

Section: Personal Recovery: Well-being and Qolmentioning

confidence: 99%

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Improving Functioning, Quality of Life, and Well-being in Patients With Bipolar Disorder

Bonnín

Reinares

Martínez‐Arán

et al. 2019

International Journal of Neuropsychopharmacology

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People with bipolar disorder frequently experience persistent residual symptoms, problems in psychosocial functioning, cognitive impairment, and poor quality of life. In the last decade, the treatment target in clinical and research settings has focused not only on clinical remission, but also on functional recovery and, more lately, in personal recovery, taking into account patients’ well-being and quality of life. Hence, the trend in psychiatry and psychology is to treat bipolar disorder in an integrative and holistic manner. This literature review offers an overview regarding psychosocial functioning in bipolar disorder. First, a brief summary is provided regarding the definition of psychosocial functioning and the tools to measure it. Then, the most reported variables influencing the functional outcome in patients with bipolar disorder are listed. Thereafter, we include a section discussing therapies with proven efficacy at enhancing functional outcomes. Other possible therapies that could be useful to prevent functional decline and improve functioning are presented in another section. Finally, in the last part of this review, different interventions directed to improve patients’ well-being, quality of life, and personal recovery are briefly described.

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Section: Personal Recovery: Well-being and Qolmentioning

confidence: 99%

Section: Personal Recovery: Well-being and Qolmentioning

confidence: 99%

Improving Functioning, Quality of Life, and Well-being in Patients With Bipolar Disorder

Bonnín

Reinares

Martínez‐Arán

et al. 2019

International Journal of Neuropsychopharmacology

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“…Quality of life (QoL) has been reported to be reduced in patients with severe mental illnesses. Awareness of the topic in psychiatric research is rising [ 1 , 2 ]. Because QoL is increasingly being used in studies as a patient-related outcome, the identification and the impact of factors influencing QoL in these patients is of special interest.…”

Section: Introductionmentioning

confidence: 99%

Quality of life in patients with severe mental illness: a cross-sectional survey in an integrated outpatient health care model

et al. 2020

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Purpose This study (a) assessed quality of life (QoL) in a patient sample with severe mental illness in an integrated psychiatric care (IC) programme in selected regions in Germany, (b) compared QoL among diagnostic groups and (c) identified socio-demographic, psychiatric anamnestic and clinical characteristics associated with QoL. Methods This cross-sectional study included severely mentally ill outpatients with substantial impairments in social functioning. Separate dimensions of QoL were assessed with the World Health Organisation’s generic 26-item quality of life (WHOQOL-BREF) instrument. Descriptive analyses and analyses of variance (ANOVAs) were conducted for the overall sample as well as for diagnostic group. Results A total of 953 patients fully completed the WHOQOL-BREF questionnaire. QoL in this sample was lower than in the general population (mean 34.1; 95% confidence interval (CI) 32.8 to 35.5), with the lowest QoL in unipolar depression patients (mean 30.5; 95% CI 28.9 to 32.2) and the highest in dementia patients (mean 53.0; 95% CI 47.5 to 58.5). Main psychiatric diagnosis, living situation (alone, partner/relatives, assisted), number of disease episodes, source of income, age and clinical global impression (CGI) scores were identified as potential predictors of QoL, but explained only a small part of the variation. Conclusion Aspects of health care that increase QoL despite the presence of a mental disorder are essential for severely mentally ill patients, as complete freedom from the disorder cannot be expected. QoL as a patient-centred outcome should be used as only one component among the recovery measures evaluating treatment outcomes in mental health care. Electronic supplementary material The online version of this article (10.1007/s11136-020-02470-0) contains supplementary material, which is available to authorized users.

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“…QoL is a broad construct taken to represent aspects of functioning and satisfaction in occupational, environmental, social, physical, and psychological aspects of life (50).QoL has not only become an increasingly important outcome parameter in clinical trials, but also a target for web-based psychoeducational self-monitoring programs (51,52). Different scales exist to make the rather holistic and fuzzy defined term "Quality of life" measurable (53).…”

Section: Impact On Quality Of Lifementioning

confidence: 99%

The Impact of Subsyndromal Bipolar Symptoms on Patient’s Functionality and Quality of Life

Grunze

Born

2020

Front. Psychiatry

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Subsyndromal symptoms have rarely been in the focus of bipolar research. This may be, in part, due to the fact that there is neither a uniform definition nor do they constitute an indication of regulatory and commercial interest. Nevertheless, they do have a decisive impact on the long-term course of bipolar disorder (BD), and the degree of functionality and quality of life (QoL) is more likely determined by their presence or absence than by acute episodes. Summarizing the literature an estimated 20-50% of patients suffer interepisodically or chronically from subsyndromal BD. The most prominent symptoms that interfere with functionality are subsyndromal depression, disturbances of sleep, and perceived cognitive impairment, whereas anxiety negatively impacts on QoL. In the absence of evidence-based pharmacological treatments for subsyndromal BD, clinical practice adopts guidelines designed for treatment-resistant full-blown episodes of BD, supplemented by cognitive-behavioral, family focused or social-rhythmbased psychotherapies.

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What does quality of life refer to in bipolar disorders research? A systematic review of the construct's definition, usage and measurement

Cited by 47 publications

References 63 publications

Improving Functioning, Quality of Life, and Well-being in Patients With Bipolar Disorder

Improving Functioning, Quality of Life, and Well-being in Patients With Bipolar Disorder

Quality of life in patients with severe mental illness: a cross-sectional survey in an integrated outpatient health care model

The Impact of Subsyndromal Bipolar Symptoms on Patient’s Functionality and Quality of Life

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