What has changed in canine pyoderma? A narrative review

Loeffler, Anette; Lloyd, D. H.

doi:10.1016/j.tvjl.2018.04.002

Cited by 84 publications

(100 citation statements)

References 129 publications

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“…In small animal veterinary practice, pyoderma is one of the leading reasons for a practitioner to prescribe systemic antimicrobial agents . Pyoderma in dogs is most commonly caused by Staphylococcus pseudintermedius with other staphylococci being involved in ≤10% of cases . These superficial infections are rarely life‐threatening but can significantly increase canine morbidity, leading to decreases in quality of life through subsequent pain, inflammation and pruritus …”

Section: Introductionmentioning

confidence: 99%

“…The increasing phenomenon of antimicrobial resistance has been documented in the veterinary literature, prompting the need for alternative therapies to systemic drugs . To avoid contributing to antimicrobial resistance, many clinicians and microbiologists advocate a shift away from systemic antibiotic use, which can be associated with bacterial resistance, towards the use of topical antiseptics that have different modes of action . Studies demonstrate good evidence that topical therapy alone can be effective in treating pyoderma .…”

Section: Introductionmentioning

confidence: 99%

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Residual antibacterial activity of canine hair treated with five mousse products againstStaphylococcus pseudintermedius in vitro

Ramos

Woodward

Hoppers

et al. 2019

Veterinary Dermatology

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Background -Topical therapy alone can be effective in the treatment of canine pyoderma. Topical products are commercially available as shampoos, sprays, wipes and mousses. To date, no studies have evaluated the efficacy of commercially available mousse products in the treatment of canine pyoderma.Objective -To determine the residual antibacterial activity of canine hairs treated with mousse products containing different active ingredients.Animals -Fifteen client-owned dogs with no history of dermatological disease.Methods and materials -Dogs were treated once with five mousse products [(i) 2% chlorhexidine and 1% ketoconazole, (ii) 2% chlorhexidine and 2% miconazole, (iii) 3% chlorhexidine and 0.5% climbazole, (iv) 2% salicylic acid 10% ethyl lactate and (v) phytosphingosine HCl 0.05%; control]. Hair samples were collected from each treatment area before application, one hour after application and on days 2, 4, 7, 10 and 14 post-treatment. Collected hairs were weighed and plated on Mueller-Hinton agar plates streaked with a Staphylococcus pseudintermedius isolate showing no antimicrobial resistance. Plates were incubated for 24 h and bacterial growth inhibition zones around the hairs were measured.Results -Mousses 1, 2 and 3 created significant inhibition zones up to Day 10 when compared to pre-treatment samples. On Day 14, only mousse 3 produced a significant zone of inhibition when compared to the pre-treatment sample. Mousses 4 and 5 showed no statistical difference between any of the samples.Conclusions and clinical importance -These results suggest that three of the mousse products had residual activity in inhibiting S. pseudintermedius growth in vitro for at least 10 days.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Residual antibacterial activity of canine hair treated with five mousse products againstStaphylococcus pseudintermedius in vitro

Ramos

Woodward

Hoppers

et al. 2019

Veterinary Dermatology

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“…This ubiquitous and urgent clinical problem concerns not only human medicine, but also veterinary practice. In companion animals, canine skin infections constitute the main reason for antibiotics use [1], and consequently, may promote the development of resistance among canine bacteria [2,3]. Coagulase-positive staphylococci (CoPS), mostly S. pseudintermedius and S. aureus, are predominant pathogens in canine pyoderma [4,5].…”

Section: Introductionmentioning

confidence: 99%

“…The antimicrobial resistance of CoPS has a key role in the management of canine skin infections. The vast majority of those diseases have a chronic character with a tendency to recur, which is reflected by prolonged systemic antibiotic therapy, associated with an alarming increase in the proportion of antibiotic-resistant staphylococci, particularly methicillin-resistant staphylococci [3,5].…”

Section: Introductionmentioning

confidence: 99%

In Vitro Efficiency of Antimicrobial Peptides against Staphylococcal Pathogens Associated with Canine Pyoderma

Jarosiewicz

Garbacz

Neubauer

et al. 2020

Animals

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The emergence of staphylococcal canine pathogens resistant to multiple antimicrobial agents is a growing and urgent problem in veterinary practice. Antimicrobial peptides (AMPs) seem to be a promising alternative to conventional antibiotics. The aim of this in vitro study was to evaluate the antimicrobial activity of selected AMPs against pathogenic staphylococcal strains, including multidrug- and methicillin-resistant strains isolated from canine pyoderma cases. Seven antimicrobial peptides (aurein 1.2, CAMEL, citropin 1.1, protegrin-1, pexiganan, temporin A and uperin 3.6) synthesized by the 9-fluorenylmethoxycarbonyl (Fmoc) solid-phase method were tested. The minimal inhibitory and minimal bactericidal concentrations (MIC and MBC) were determined by the broth microdilution method. The study showed that analyzed AMPs exerted an extensive effect against canine pathogens, with the most active peptide being uperin 3.6. The tested AMPs were equally efficient against both resistant- and susceptible staphylococcal strains and were more efficient against Staphylococcus pseudintermedius than against Staphylococcus aureus strains. Our findings are particularly interesting from a clinical perspective, as they point to AMPs as potential therapeutic topical agents in canine pyoderma cases associated with antimicrobial resistance of staphylococci.

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“…Neste estudo, tivemos seis agentes multirresistentes isolados da infecção necrotizante de pele e tecidos moles dos cães. Este resultado novamente põem em destaque o potencial zoonótico, o aumento da dificuldade no tratamento desses casos, bem como fomenta a preocupação mundial em relação a saúde pública já relatada previamente (MAGIORAKOS et al, 2011;VAN DUIN;MORRIS et al, 2017, LOEFFLER;LLOYD, 2018).…”

Section: Antibiogramaunclassified

>b<Investigação anatomopatológica e microbiológica de fascites necrotizantes letais em cães:>/b< há implicações em saúde pública?

Ríspoli¹

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Aos colegas da pós Força aí galera, to na torcida! Agradeço aos Tutores que permitiram o uso dos dados de seus amados companheiros para sabermos mais sobre à FN. Entendo a dor e desespero que passaram, Estou (e estive) junto. Infelizmente, não ganhamos a batalha, Mas a Guerra não está perdida, Doeu tanto e de tal forma, Que gostaria de ter dado qualquer coisa pela vida deles, A perda foi tamanha e inestimável, Que dói demais relembrar, Mas estejamos juntos para evitar novas derrotas E que nada disso tenha sido em vão.

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What has changed in canine pyoderma? A narrative review

Cited by 84 publications

References 129 publications

Residual antibacterial activity of canine hair treated with five mousse products againstStaphylococcus pseudintermedius in vitro

Residual antibacterial activity of canine hair treated with five mousse products againstStaphylococcus pseudintermedius in vitro

In Vitro Efficiency of Antimicrobial Peptides against Staphylococcal Pathogens Associated with Canine Pyoderma

>b<Investigação anatomopatológica e microbiológica de fascites necrotizantes letais em cães:>/b< há implicações em saúde pública?

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