What is the influence of complement factor C3 and lipid metabolism of adipose tissue on hepatic steatosis in mice?

Abstract

NALFD (non-alcoholic fatty liver disease) represents a fatty liver whereby lipid accumulation (steatosis) occurs. In recent decades, the prevalence of NAFLD has dramatically increased.Activation of the complement system, which is an important subset of the immune system, and especially complement factor C3, may have a significant role in the progression mice on a HFD. However it seems that lipids do not only accumulate by C3 activation,