What Is the Optimal Clinical Technique for Measurement of Left Ventricular Volume After Myocardial Infarction? A Comparative Study of 3-Dimensional Echocardiography, Single Photon Emission Computed Tomography, and Cardiac Magnetic Resonance Imaging

Chan, Jonathan; Jenkins, Carly; Khafagi, Frederick A.; Du, Leanne; Marwick, Thomas H.

doi:10.1016/j.echo.2005.08.020

Cited by 66 publications

(46 citation statements)

References 16 publications

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“…The correlation coefficients between MPS and CMR for LV volumes and EF were similar between Segment and the four other MPS software packages, and in line with results reported in earlier studies [10][11][12][13]16,[14][15][17][18][19]. In the current study the EDV and ESV were underestimated by MPS, as compared to CMR, when using QGS, MyoMetrix, ECTb and Exini.…”

Section: Comparison Between Mps Software Packagessupporting

confidence: 91%

“…In the current study the EDV and ESV were underestimated by MPS, as compared to CMR, when using QGS, MyoMetrix, ECTb and Exini. This underestimation has been observed in previous studies, with the same magnitude [12][13] or with a lower magnitude [11,10,15]. The lower magnitude of the underestimation may be explained by older turbo gradient echo CMR sequences in those studies compared to the current standard SSFP imaging that was used in the current study.…”

Section: Comparison Between Mps Software Packagessupporting

confidence: 76%

“…Several previous studies have compared LV volumes quantified by those algorithms to the reference standard, cardiac magnetic resonance (CMR) [9]. In the majority of the studies the end-diastolic volume (EDV) and end-systolic volume (ESV) were underestimated by MPS [10][11][12][13][14][15]. End-diastolic volume by MPS has also been shown to range from overestimation to underestimation compared to CMR depending on the software package used [16][17][18].…”

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confidence: 99%

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Development and validation of a new automatic algorithm for quantification of left ventricular volumes and function in gated myocardial perfusion SPECT using cardiac magnetic resonance as reference standard

Soneson

Hedeer

Arévalo

et al. 2011

Journal of Nuclear Cardiology

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Section: Comparison Between Mps Software Packagessupporting

confidence: 91%

Section: Comparison Between Mps Software Packagessupporting

confidence: 76%

mentioning

confidence: 99%

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Development and validation of a new automatic algorithm for quantification of left ventricular volumes and function in gated myocardial perfusion SPECT using cardiac magnetic resonance as reference standard

Soneson

Hedeer

Arévalo

et al. 2011

Journal of Nuclear Cardiology

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“…Nevertheless, to date, quantitative assessment of LV remodeling has been predominantly described in terms of changes in LV volume and ejection fraction, while disregarding the simultaneously occurring changes in ventricular shape. While a variety of techniques for quantitative evaluation of LV volume have become part of standard clinical practice [1][2][3], the development of tools for quantitative evaluation of ventricular shape has been explored only partially [4][5][6][7]. This is despite several studies indicating that LV shape analysis may be potentially useful and could be used in conjunction with different imaging modalities, including radionuclide ventriculography [8,9], electron beam computed tomography [10] and ultrasound images [11][12][13][14].…”

Section: Introductionmentioning

confidence: 99%

Three-dimensional analysis of regional left ventricular endocardial curvature from cardiac magnetic resonance images

Maffessanti

Lang

Niel

et al. 2011

Magnetic Resonance Imaging

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Purpose: Left ventricular (LV) remodeling is usually assessed using global changes in LV volume. We hypothesized that threedimensional analysis of regional endocardial curvature from magnetic resonance images could provide clinically useful information on localized LV remodeling. We tested this approach by investigating regional differences in endocardial curvature in normal and hypokinetic ventricles. Materials and Methods: Images were obtained in 44 patients with normal LV function (NL, N=14), dilated cardiomyopathy (DCM, N=15) or ischemic heart disease (IHD, N=15). Local surface curvedness, normalized to take into account instantaneous LV size (C n ), was calculated throughout the cardiac cycle and compared between segment groups: NL (N=401), IHD (N=92) and DCM (N=255). Results: In all normal segments, C n gradually increased during systole and then decreased during diastole. While both maximum and minimum values of C n were comparable in the basal and midventricular segments, they were significantly higher in the four apical segments and highest in the apical cap. In addition, percent change in C n was higher in mid and apical compared to basal segments (Pb.05). At all LV levels, C n values in DCM segments were lower (Pb.05) than in NL and IHD segments, which were similar. In contrast, percent change in C n was significantly lower in both IHD and DCM segments compared to NL. Conclusion: Three-dimensional analysis of LV endocardial curvature yielded quantitative information on regional ventricular shape consistent with the known pathophysiology, supporting its potential clinical usefulness in the evaluation of LV remodeling.

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“…While the value of ECG-gated SPECT in assessing myocardial perfusion is well established, there are fewer data on the accuracy of ECG-gated SPECT for estimating left ventricular(LV) volumes and ejection fraction (EF) particularly in patients with severe and multiple perfusion defects caused by ischemic cardiomyopathy (Lim et al, 2006;Ioannidis et al, 2002;Chan et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Comparison of cardiac magnetic resonance with gated SPECT for evaluation of left ventricular function and volumes in patients with severe and multiple myocardial perfusion defects

Fathala

2010

Journal of the Saudi Heart Association

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Objectives: Gated SPECT is an accurate technique for assessment of myocardial perfusion (MP), left ventricular ejection fraction (LVEF), end-diastolic volume (EDV) and end-systolic volume (ESV). However recent studies have concluded that there are large discrepancies in assessment of LVEF and volumes by gated SPECT in patients with multiple severe myocardial perfusion defects. We sought to investigate the correlation between LVEF and volumes calculated by gated SPECT and cardiac magnetic resonance (CMR) in patients with severe multiple perfusion defects who are referred for CMR. Methods: Twenty-nine patients (20 male and 9 female, mean age: 63 years ± 11) with multiple severe fixed perfusion defects (mean 5 ± 3 segments) were referred to undergo CMR. The average time between CMR and SPECT was 4 weeks. LVEF, EDV, and ESV were derived automatically from gated SPECT. In the CMR studies, the endocardial and epicardial borders were delineated manually in the short axis planes to calculate the LVEF and volumes. Results: The different parameters were compared using linear regression, and correlation coefficients were calculated. Substantial correlation was found between CMR and gated SPECT for EDV: r = 0.7, p < 0.001. Moderate correlation between CMR and gated SPECT for LVEF: r = 0.5, p < 0.007 and ESV r =0 .53, p < 0.003. Conclusion: Our data showed that the gated SPECT correlates substantially with MRI for measurement of EDV and moderately for ESV and LVEF in patients with multiple and severe perfusion defects. Thus, when accurate measurement is required, cardiac MRI is recommended.

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What Is the Optimal Clinical Technique for Measurement of Left Ventricular Volume After Myocardial Infarction? A Comparative Study of 3-Dimensional Echocardiography, Single Photon Emission Computed Tomography, and Cardiac Magnetic Resonance Imaging

Cited by 66 publications

References 16 publications

Development and validation of a new automatic algorithm for quantification of left ventricular volumes and function in gated myocardial perfusion SPECT using cardiac magnetic resonance as reference standard

Development and validation of a new automatic algorithm for quantification of left ventricular volumes and function in gated myocardial perfusion SPECT using cardiac magnetic resonance as reference standard

Three-dimensional analysis of regional left ventricular endocardial curvature from cardiac magnetic resonance images

Comparison of cardiac magnetic resonance with gated SPECT for evaluation of left ventricular function and volumes in patients with severe and multiple myocardial perfusion defects

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