Abstract-We investigate the impact of cooperative relaying used to create virtual multipoint-to-point links (as opposed to conventional multihop relaying) on the throughput optimal configuration of a wireless network. We achieve this by formulating a cross-layer framework for a joint routing and scheduling problem with cooperative relaying. We consider a general case, where cooperation is allowed between any pair of nodes in a given network. We optimally solve this formulation for max-min throughput in mesh-like networks of medium size and quantify gains for key performance metrics. We establish that, contrary to popular belief, cooperative relaying provides performance gains in a mid-size network surprisingly rarely. Moreover, if gains can be obtained, these gains are typically only marginal. We quantify these gains and provide engineering insights based on numerical results for 200 random realizations of a network with 16 nodes.