What is the role of diagnostic laparoscopy in a gastroenterology unit?

Yoon, Young Joon; Ahn, Sang Hoon; Park, Jun Yong; Chon, Chae Yoon; Kim, Do Young; Park, Young Nyun; Han, Kwang Hyub

doi:10.1007/s00535-007-2106-0

Cited by 12 publications

(9 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…On the other hand, peritoneal tuberculosis was diagnosed in 4/30 (13.3%) of cases and pancreatitis in 1/30 (3.3%). Compared to our results, [18] had studied patients with ascites of unknown origin by laparoscopy and found the diagnostic yield was 87.2%. The confirmed diagnoses were peritoneal carcinomatosis in 60.5%, TB peritonitis in 20.2%, and cirrhosis in 5.4%.…”

Section: Discussioncontrasting

confidence: 72%

Diagnostic value of a panel of tumor markers as a part of a diagnostic work-up for ascites of unknown etiology

Abdelmoniem¹,

Zaki²,

Imam³

et al. 2012

OJGas

View full text Add to dashboard Cite

Background & objectives: Data regarding tumor marker usefulness in diagnosing ascites of unknown etiology and determining its malignant nature are conflicting. We aim to assess the diagnostic value of ascitic and serum tumor markers in ascites of unknown etiology and to evaluate their usefulness besides other laboratory tests in a diagnostic work-up in those patients. Design & setting: A prospective case-control study conducted at Assiut University hospital and oncology institute. Patients & Methods: Three groups were included; Group I: 41 patients with ascites of unknown etiology Group II: 7 Patients with TB ascites and Group III:14 patients with cirrhotic ascites. We assessed the CEA, CEA mRNA, CA15-3, CA19.9, CA125, AFP and PSA in serum and ascetic fluid. A diagnostic work-up for group I included: IPD test, ultrasound, CT, ascetic fluid cytology, SAAG, Laparotomy and biopsy. Results: Ascetic fluid and serum levels of CA15-3 and CA125 were significantly increased in group I and were significantly increased in histopathologically proved malignant ascites compared to TB and cirrhotic ascites. In group I, CA 125 was significantly higher in ascites than serum. With the exception of PSA, all tumor markers significantly correlated in serum and ascetic fluid. No significant difference in the level of ascetic CEA messenger RNA was detected between the 3 groups. Cytology had 53% sensitivity, 94% specificity and CA 125 & CA15-3 had 81% sensitivity and 75% specificity in detection of malignant ascites repectively. Laparotomy and biopsy: diagnosed malignnancy in 53.3% and TB in 13.3%. Conclusions: A diagnostic work-up including SAAG, tumor markers in the serum and ascetic fluid may help in adjunct with ascetic fluid cytology, laparotomy and biopsy, imag- ing and other laboratory tests in diagnosing ascites of unknown etiology

show abstract

Section: Discussioncontrasting

confidence: 72%

Diagnostic value of a panel of tumor markers as a part of a diagnostic work-up for ascites of unknown etiology

Abdelmoniem¹,

Zaki²,

Imam³

et al. 2012

OJGas

View full text Add to dashboard Cite

show abstract

“…In comparison to open abdominal exploration, the incidence of complications for the laparoscopy technique was extremely low [14] . Considering the high diagnostic efficacy of laparoscopy, the complication rate of this micro-invasive method seems to be acceptable.…”

Section: Safety Of Mini-laparoscopymentioning

confidence: 99%

Diagnostic value of mini-laparoscopy in patients with abdominal neoplasm

Wang

Chen

2011

Chin. J. Cancer Res.

View full text Add to dashboard Cite

Objective: Blood biochemistry, ascites tests, and imaging examinations have low sensitivities in abdominal neoplasm diagnoses. In addition, exploratory laparotomy is not suitable for final stage patients. Mini-laparoscopy has recently emerged as a new diagnostic technology for abdominal disease. The aim of this research was to evaluate the value of mini-laparoscopy in diagnosing abdominal neoplasms.Methods: Clinical and operational data were retrospectively analyzed in 20 cases with pathologically confirmed abdominal malignancies. Of these, 10 cases were each diagnosed by mini-laparoscopy and exploratory laparotomy. The surgical and anesthesia expenses, perioperative nursing, monitoring and treating charges, postoperative hospital stay and complications were compared between groups.Results: The surgical and anesthesia costs were statistically lower in patients who received a mini-laparoscopy (P<0.01). Perioperative drug expenses and nursing and monitoring charges were also significantly decreased (P<0.05 and P<0.01, respectively). Further, the gastrointestinal function recovery time and postoperative hospital stay were significantly reduced in the mini-laparoscopy group. There was no significant difference between the two groups regarding the preoperative hospital stay and postoperative complications.Conclusion: Mini-laparoscopy effectively reduces surgical injury and treatment costs, and is capable of safely diagnosing abdominal tumors. Moreover, the procedure is also easy to perform.

show abstract

“…Diagnostic laparotomy provides ground for effective diagnosis of peritoneal carcinomatosis, tuberculous peritonitis, etc. [43,44].…”

Section: Diagnostic Laparotomymentioning

confidence: 99%

Review on Ascites in Pets

Nwoha¹

2020

Veterinary Medicine and Pharmaceuticals

View full text Add to dashboard Cite

Ascites is one of the major complications seen in various disease conditions in pets. Ascites is characterised by distension of the abdomen with accumulation of fluid of various colours and consistencies depending on the cause. The most common causes of ascites in pets include but not limited to the following health conditions: hypoproteinaemia, left-sided heart failure, congestive heart failure, cirrhosis, hepatic diseases, renal diseases, ancylostomosis and bacterial infection such as tuberculosis. Pathogenesis of ascites often emanate from portal hypertension, cirrhosis, hepatorenal syndrome, etc. Oftentimes the diagnosis of ascites could be cumbersome considering the myriad of diseases implicated in the condition. Standard diagnostic procedures include the following: physical examination, clinical examination, ultrasonography, computed tomography, serum ascites albumin gradient (SAAG), biochemical analysis such as triglyceride, urea and creatinine concentration, total protein, etc. Novel diagnostic procedures with possible clinical relevance include the following: leucocyte esterase reagent strip, platelet indices, tumour markers, etc. Diagnosis is made through standard diagnostic procedure, while special cases of idiopathic origin are detected through diagnostic laparotomy. Novel diagnostic procedures such as platelet indices, leucocyte esterase reagent strip and tumour markers would aid in easy diagnosis of ascites. Treatment of ascites is dependent on identification of the cause of ascites.

show abstract

What is the role of diagnostic laparoscopy in a gastroenterology unit?

Abstract: Diagnostic laparoscopy in a gastroenterology unit is safe and useful, especially for confirmation of liver cirrhosis and primary peritoneal disease evaluation.

Cited by 12 publications

References 29 publications

Diagnostic value of a panel of tumor markers as a part of a diagnostic work-up for ascites of unknown etiology

Diagnostic value of a panel of tumor markers as a part of a diagnostic work-up for ascites of unknown etiology

Diagnostic value of mini-laparoscopy in patients with abdominal neoplasm

Review on Ascites in Pets

Contact Info

Product

Resources

About