What is the value of cystoscopy with hydrodistension for interstitial cystitis?

Ottem, Derek P.; Teichman, Joel M.H.

doi:10.1016/j.urology.2005.04.011

Cited by 140 publications

(98 citation statements)

References 25 publications

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“…In a study of 47 adult women with IC/BPS, the average voided volume was less than 100mL. 19 On average, IC/BPS patients void a volume of urine ranging from 86-174mL, compared to an average of 289 mL in an asymptomatic woman. The average number of daytime voids ranges from 17-25 compared to six.…”

Section: Ultrasound/pelvic Imaging (Optional Select Patients Grade mentioning

confidence: 99%

CUA guideline: Diagnosis and treatment of interstitial cystitis/ bladder pain syndrome

Cox

Golda

Nadeau

et al. 2016

CUAJ

115

121

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MethodologyThe following guidelines were based on MEDLINE and PUBMED searches of English language literature, in addition to consensus conference proceedings. Levels of evidence and grades of recommendation were assigned for each investigation and treatment, as per the modified Oxford Centre for Evidence-Based Medicine grading system. Where the literature was inconsistent or scarce, a consensus expert opinion was generated to provide treatment guidelines.

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Section: Ultrasound/pelvic Imaging (Optional Select Patients Grade mentioning

confidence: 99%

CUA guideline: Diagnosis and treatment of interstitial cystitis/ bladder pain syndrome

Cox

Golda

Nadeau

et al. 2016

CUAJ

115

121

View full text Add to dashboard Cite

show abstract

“…Hydrodistension of the bladder has been shown to temporarily improve symptoms and pain by 56%, but only lasting for a mean duration of two months. 16 Resection, fulguration or laser of Hunner's ulcer can produce symptom relief initially in around 90%, sustained in 40% at three years (although patients may need repeat treatments and bladder perforation is a risk). 17 In combination with hydrodistention, this treatment can improve symptoms for around 28 months.…”

Section: Surgical Optionsmentioning

confidence: 99%

The challenge of bladder pain syndrome

Alnajjar¹,

Biers²

2017

Trends Urology & Men Health

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“…Although somewhat controversial, some studies suggest that endoscopic hydrodistention has (short term) efficacy in the treatment of PBS/IC symptoms. Ottem & Teichman, retrospectively reviewed 84 consecutive PBS/IC patients treated with hydrodistension and found over 50% reported symptomatic improvement 2 months after the procedure (19). Unfortunately, however, it is difficult to generalize results from hydrodistension studies due to variance in techniques and outcome reporting.…”

Section: Commentsmentioning

confidence: 99%

Multimodal therapy for painful bladder syndrome / interstitial cystitis: pilot study combining behavioral, pharmacologic, and endoscopic therapies

et al. 2009

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Purpose:We evaluated the effectiveness of combining behavioral therapy, pharmacologic therapy and endoscopic hydrodistension for treating painful bladder syndrome / interstitial cystitis (PBS/IC). Materials and Methods: Twenty-five patients with PBS/IC were prospectively enrolled in a pilot multimodal behavioral, pharmacologic and endoscopic treatment protocol. Behavioral modification included diet recommendations, fluid restriction to 64 oz. /day, progressive timed voiding and Kegel exercises. Oral pharmacologic therapy consisted of daily doses of macrodantin 100 mg, hydroxyzine 10-20 mg and urised 4 tablets. Patients underwent endoscopic bladder hydrodistention under anesthesia at least 2 weeks after protocol enrollment. Behavioral and pharmacological treatments were continued after the hydrodistention. O'Leary-Sant questionnaire scores were recorded before starting the protocol, after pharmacologic/behavioral therapy, 2 months post-hydrodistension, and at scheduled follow-up. Results: Eighteen patients (72%) completed the pilot multimodal treatment protocol and were followed for a mean of 10.2 months. All patients were female with a median age of 36.3 years and had mean bladder capacity under anesthesia of 836 milliliters. Mean O'Leary-Sant symptom index scores for baseline symptoms, after behavioral/pharmacologic treatment, post-hydrodistension and during follow up were 12.5, 8.6, 7.0, and 6.7 (p < 0.05). Mean O'Leary-Sant problem index scores for baseline, after behavioral/pharmacologic treatment, post-hydrodistention and during follow up were 12.7, 8.9, 6.7, and 7.7 (p < 0.05). Conclusion: Our pilot multimodal protocol of behavioral modification, pharmacologic therapy and endoscopic hydrodistention demonstrated a significant progressive improvement in PBS/IC quality of life scores, compared to a pre-treatment baseline. These results should be validated in a larger, placebo controlled trial.

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What is the value of cystoscopy with hydrodistension for interstitial cystitis?

Cited by 140 publications

References 25 publications

CUA guideline: Diagnosis and treatment of interstitial cystitis/ bladder pain syndrome

CUA guideline: Diagnosis and treatment of interstitial cystitis/ bladder pain syndrome

The challenge of bladder pain syndrome

Multimodal therapy for painful bladder syndrome / interstitial cystitis: pilot study combining behavioral, pharmacologic, and endoscopic therapies

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