Purpose: The problematic of functions and responsibilities' distribution of the public and private sectors is a debatable issue in the study of the most effective PPP models. The objective of this academic paper is to study the features of the application of public-private partnership for the purpose of implementing state policy in the sphere of health care. Design/Methodology/Approach: Based on the in-depth case study for data collection and semi-structured in-depth interview, detailed data on the experience of PPP projects in Ukraine have been collected and analysed with statistical methods. Findings: As a result, the problem of implementing the PPP model has been revealed being the impossibility of municipal authorities to provide guarantees of funds' return to a private partner. This problem is common in the countries with transition economies, where the concept of new public governance has not been implemented yet. The experience of Italy and China as an example of effective implementation of hybrid PPP models in the health care sphere has been studied. Originality/Value: Research proves the importance of compliance with the obligations of the municipality and its active participation in the implementation of the PPP project. The basic limitation is the inability to scale the results, the experience of the PPP project to other regions within countries due to the lack of practice of implementing the PPP mechanism.