What neurological and psychiatric effects does COVID-19 have on its survivors?

Mentis, Alexios‐Fotios A.

doi:10.1186/s12916-021-01986-7

Cited by 3 publications

(2 citation statements)

References 6 publications

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“…Our study revealed that the participants’ perception of COVID-19 affecting their lives (consequences) led to the use of CAM. COVID-19 has resulted in the significant loss of many lives globally, an increase in unemployment rates, a reduction in food security as well as self-isolation of infected individuals ( Piltch-Loeb et al, 2021 , Aliakbari Dehkordi et al, 2020 , VanderWeele, 2020 , Yang et al, 2020 , Mentis, 2021 ). These consequences are likely reasons for people’s use to CAM for COVID-19 prevention.…”

Section: Discussionmentioning

confidence: 99%

Utilization of complementary and alternative medicine for the prevention of COVID-19 infection in Ghana: A national cross-sectional online survey

Kretchy¹,

Boadu²,

Kretchy³

et al. 2021

Preventive Medicine Reports

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Section: Discussionmentioning

confidence: 99%

Utilization of complementary and alternative medicine for the prevention of COVID-19 infection in Ghana: A national cross-sectional online survey

Kretchy¹,

Boadu²,

Kretchy³

et al. 2021

Preventive Medicine Reports

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“…In addition, a plausible role of saffron on reducing anxiety and depression, most likely through inhibition of monoaminoxidase-b, has been proposed [ 41 , 46 ]. Therefore, the potential benefits of saffron could hold promise during the COVID-19 pandemic, particularly in the treatment of psychiatric and neurologic sequelae of the post-COVID syndrome [ 47 ].…”

Section: Current Evidence On Saffron In Covid-19-related Cytokine Stormmentioning

confidence: 99%

Saffron for “toning down” COVID-19-related cytokine storm: Hype or hope? A mini-review of current evidence

Mentis

Dalamaga

et al. 2021

Metabolism Open

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Aim To assess the potential role of saffron in downregulating inflammation and cytokine storm during COVID-19. Main findings Three main compounds of saffron, i.e., crocetin esters, picrocrocin, and safranal, present strong antioxidant and anti-inflammatory action for several disease states (e.g., Alzheimer's, cancer, and depression) but have also been studied in COVID-19. In particular, based on our comprehensive review of both in vitro and in silico studies, saffron's essential oils and other constituents appear to have both immunomodulatory and anti-asthmatic actions; these actions can be particularly helpful to treat patients with respiratory symptoms due to COVID-19. Moreover, crocin appears to reduce the COVID-19-related cytokine cascade and downregulate angiotensin-converting enzyme 2 ( ACE2 ) gene expression. Last, in silico studies suggest that saffron's astragalin and crocin could have inhibitory actions on SARS-CoV-2 protease and spike protein, respectively. Conclusion Saffron represents a promising substance for toning down cytokine storm during COVID-19, as well as a potential preventive treatment for COVID-19. However, appropriate randomized clinical trials, especially those using biomarkers as surrogates to assess inflammatory status, should be designed in order to assess the clinical efficacy of saffron and allow its use as an adjunct treatment modality, particularly in resource-poor settings where access to drugs may be limited.

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Analyzing the Human Rights Impact of Increased Digital Public Health Surveillance during the COVID-19 Crisis

2020

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What neurological and psychiatric effects does COVID-19 have on its survivors?

Cited by 3 publications

References 6 publications

Utilization of complementary and alternative medicine for the prevention of COVID-19 infection in Ghana: A national cross-sectional online survey

Utilization of complementary and alternative medicine for the prevention of COVID-19 infection in Ghana: A national cross-sectional online survey

Saffron for “toning down” COVID-19-related cytokine storm: Hype or hope? A mini-review of current evidence

Analyzing the Human Rights Impact of Increased Digital Public Health Surveillance during the COVID-19 Crisis

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