Background
Improved PrEP uptake is essential for HIV prevention initiatives. Offering PrEP at the time of HIV and STI testing can improve uptake. We offered rapid PrEP initiation in a sexual health clinic and assessed predictors of PrEP interest, initiation, linkage, and retention.
Methods
Between November 2018 and February 2020, PrEP-eligible individuals who presented to a sexual health clinic were offered a free 30-day supply of PrEP plus linkage to continued PrEP care. Univariable and multivariable analyses of demographic and HIV risk data were conducted to determine predictors of PrEP uptake.
Results
Out of 1,259 PrEP-eligible adults (99.7% male, 42.7% White, 36.2% Hispanic): 456 were interested in PrEP, 249 initiated PrEP, 209 were linked, and 67 were retained in care. Predictors of PrEP interest included younger age (p<0.01), lower monthly income (p=0.01), recreational drug use (p=0.02), and a greater number of sexual partners (p<0.01). Negative predictors of PrEP initiation included lower monthly income (p= 0.04), testing positive for chlamydia (p=0.04), and exchanging money for sex (p=0.01). Negative predictors of linkage included self-identifying as Black (p=0.03) and testing positive for an STI (p<0.01). Having health insurance positively predicted both linkage (p<0.01) and retention (p<0.03).
Conclusions
A minority of PrEP-eligible HIV and STI testers initiated PrEP when offered, suggesting that easy PrEP access in sexual health clinics may not alone improve uptake. Predictors of uptake included established HIV risk factors and markers of higher socioeconomic status, suggesting that those aware of their risk and with the means to utilize health services engaged best with this model.