What should be taken into account during study on immunoregulatory effects of helminths: a critical analyzing on “Downregulation of immune responses in asthmatic patients by ES products of Marshallagia marshalli”

A brief commentary on ‘Response letter to “What should be taken into account during study on immunoregulatory effects of helminths: a critical analyzing on downregulation of immune responses in asthmatic patients by ES products of Marshallagia marshalli”’

“…To clarify, in the previous letter, it has been indicated to the presence of LPS in the abomasum of sheep, not the existence of live bacteria (resident bacteria) in this organ. In addition, contamination of worms and their cuticle with rumen fluids containing a huge amount of gram negative bacteria and LPS during collecting abomasums from abattoir is an indispensable matter.…”

“…Borji et al . have recently published a Letter to the Editor in response to the previous critical letter on their original paper in The Clinical Respiratory Journal. This commentary letter aims to criticize their response letter via indicating to important notes which seem to have been ignored by Borji and colleagues.…”