What should we do about Coronary Calcification on Thoracic CT?

Abstract

Purpose Coronary artery calcification is a frequent incidental finding on thoracic computed tomography (CT) performed for non-cardiac indications. On electrocardiogram-gated cardiac CT, it is an established marker of coronary artery disease and is associated with increased risk of subsequent cardiac events. Materials and Methods This review discusses the current evidence and guidelines regarding the reporting of coronary artery calcification on non-electrocardiogram-gated thoracic CT performed for non-cardiac indications. Results For patients undergoing routine thoracic CT, coronary artery calcification is associated with an increased risk of myocardial infarction and mortality. Coronary artery calcification can be accurately assessed on non-gated thoracic CT compared to gated CT. Guidelines support the reporting of coronary artery calcification on thoracic CT. However, radiologist opinions vary. The identification of coronary artery calcification on thoracic CT may identify patients with previously unknown coronary artery disease. For asymptomatic patients this may trigger an assessment of modifiable cardiovascular risk factors and guide the appropriate use of preventative medications. Conclusion Future research will address whether changing management based on calcification on thoracic CT will improve outcomes and automated assessment of calcification using machine learning techniques. Key Points: Citation Format

Importance of incidental coronary artery calcification in early diagnosis of obstructive coronary artery disease

“…Numbers and percentages were used for categorical variables. Previous studies defined a WS of ≥ 7 as severe calcification [6,7]. Therefore, the patients were divided into 2 groups: those with a WS of < 7 and those with a WS of ≥ 7.…”

“…Coronary artery calcification has been found to be the most robust risk prediction tool for CAD events, and it serves as the basis for new concepts, such as coronary and cardiovascular age, to improve risk communication between health care providers and patients [5]. Patients' awareness of their own coronary calcium burden may also potentially play a role in convincing people to make correct lifestyle choices [6] and to improve compliance with disease-modifying medications [7]. As a result, this may trigger an assessment of modifiable cardiovascular risk factors and guide the appropriate use of preventative medications [7].…”

“…Patients' awareness of their own coronary calcium burden may also potentially play a role in convincing people to make correct lifestyle choices [6] and to improve compliance with disease-modifying medications [7]. As a result, this may trigger an assessment of modifiable cardiovascular risk factors and guide the appropriate use of preventative medications [7].…”