What to Look Out for in a Newborn with Multiple Papulonodular Skin Lesions at Birth

Fraïtag, Sylvie; Boccara, O.

doi:10.3390/dermatopathology8030043

Cited by 7 publications

(2 citation statements)

References 40 publications

(47 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The differential diagnoses for soft tissue masses includes neurofibroma, sarcoma, metastatic neuroblastoma, and other neoplasms (like congenital childhood fibrosarcoma and inflammatory myofibroblastic tumor), dermoid or epidermoid tumors. Histological examination of biopsies or resected tumors remains the gold standard method for diagnosis [ 24 ].…”

Section: Discussion–literature Reviewmentioning

confidence: 99%

Prenatally Diagnosed Infantile Myofibroma of Sartorius Muscle—A Differential for Soft Tissue Masses in Early Infancy

Popa

Apostol²,

Bîcă

et al. 2021

Diagnostics

View full text Add to dashboard Cite

Background: Infantile myofibromatosis (IM) is a soft tissue disease with solitary or multiple benign tumors, and an etiology still unknown. IM is a mesenchymal disorder of early infancy and is more frequent in males. IM may present as a solitary lesion of the skin, bone, muscle, subcutaneous tissue, located at the head, neck, and trunk, with good prognosis; or, as a multicentric form, with or without visceral involvement (heart, lung, gastrointestinal tract, kidney), with a poor prognosis. The definitive diagnosis of IM is confirmed by pathology. Treatment may be conservative, surgical, or chemotherapeutical. Case presentation: A two months old female patient, prenatally diagnosed at 30 weeks, presenting with a tumor on the antero-internal aspect of the left thigh. She was admitted due to rapid postnatal evolution, and the patient required surgery for tumor resection. Previously, clinically, biological and imaging investigations were performed, but the final diagnosis was histological and by immunostaining. The patient had a favorable postoperative outcome. Conclusions: Despite its low frequency, IM should be considered in the differential diagnosis of soft tissue masses at an early age. The clinical form (solitary or multicentric), location, and visceral involvement will dictate the treatment and prognosis.

show abstract

Section: Discussion–literature Reviewmentioning

confidence: 99%

Prenatally Diagnosed Infantile Myofibroma of Sartorius Muscle—A Differential for Soft Tissue Masses in Early Infancy

Popa

Apostol²,

Bîcă

et al. 2021

Diagnostics

View full text Add to dashboard Cite

show abstract

“…A skin biopsy should always be part of the initial examination because the lesion’s histology will guide the recommendations for further investigations and the patient’s clinical management. This review summarizes the clinical and pathological features of the various disorders that may manifest at birth as multiple skin lesions, and provides the reader with numerous clinical and histological photos [ 17 ].…”

mentioning

confidence: 99%