At a time of great dynamism among publishers of scientific publications, with the inevitability of Open Access and the ease of publishing online at low cost, it is possible to find publications with different levels of scientific respectability. In this context, the improvement of the quality of scholarly publications emerges as a critical element for publishers, authors and academic institutions, as well as for society in general. This opinion piece discusses Open Access journals with different levels of quality, focusing on the following quality-promoting measures: blacklists, author’s preparation, and institutional prevention. The analysis allows concluding that the open review will be one of the key elements in the process of clarification and promotion of the level of quality and consequent scientific respectability of each of the Journals, of the thousands currently existing, a number that is likely to increase.