Introduction: Rangeland ecosystems provide multiple ecosystem services, including feed resources for wild and domestic herbivores in semi-arid areas. However, under the ever increasing environmental changes, the impact of rainfall variability on the productivity and vegetation dynamics of rangelands are the great challenges that pastoral community are facing today. As a result, the potentials of most rangelands in semi-arid ecosystems affect the livestockproduction. Therefore, we studied the interconnections between the long-term rainfall variation and the rangeland Water Requirement and Satisfaction Index (WRSI) in Mieso, Jigjiga, and Shinile districts under pastoral conditions of Ethiopia. Methods: The base period rainfall data (1984-2015) was obtained from the National Meteorological Agency of Ethiopia, whereas the future rainfall trend was predicted using MarkSim software (Representative Concentration Pathways 4.5 GHG concentration trajectory). Mann-Kendall's statistical tests, coefficient of variation, LEAP software (version 2.61), and Minitab Software (version 15) were used to assess the relationship between rangeland WRSI and long-term rainfall variability. Results: The result indicated that mean annual rainfall anomaly had strong positive correlation with rangeland WRSI in Mieso (P < 0.05), Jigjiga (P < 0.001), and Shinile (P < 0.001) pastoral areas. Similarly, short and long rainy seasons had positive association (P < 0.001) with rangeland WRSI, especially in Jigjiga and Shinile pastoral districts. The base period rainfall as well as the predicted annual rainfall showed variability in amount and distribution in all studied districts in pastoral areas of Ethiopia. Conclusions: The mean annual rainfall anomaly is correlated with the rangeland WRSI. Moreover, the future rainfall trend analysis indicated that variability of rainfall would be expected in between the years 2020-2049, 2040-2069, and 2070-2099. Thus, the future rainfall variability would limit future rangeland WRSI under pastoral conditions of Ethiopia. Based on our study, we suggested establishment and implementation of early warning systems to reduce the likely impact of rainfall variability on future rangeland potential in dry lands under the pastoral production systems in eastern Ethiopia.