The centrifugation process for the separation and/or the clarification of food and chemical liquids, requires complex and expensive machines called centrifugal separator. For example, the insertion of an expensive gear-box between the electric motor and the body of the separator and a longer starting time (about 10 min) are required. In an attempt to solve these two problems, in this work, the use of a modern multi-phase motor supplied by a variable-frequency drive (VFD) and without the gear-box has been considered. About the starting phase and the corresponding unsteady-state condition, a dynamic analysis of the traditional system, in comparison to the proposed one, was conducted. Thus, the starting time for the two cases was compared. The system with variable-frequency drive (VFD) presented a lower time (-16%) compared to the traditional one. This reduction of the starting time was found to be greater if the motor allows a starting phase with overload (-42%). Furthermore, through the equations obtained from the dynamic analysis, the starting time has been correlated with the rated power of the motor. By maintaining the high starting time in about 10 min, the equations give a halving of rated power of motor + VFD overloaded, compared to the traditional system, with a further advantage on the reduction of investment costs.