This paper is devoted to the development and evaluation of wheels-off time estimation and selection of airports without advanced automation that could benefit from wheels-off time estimation. After eliminating non-hub, small-hub, and airports with Airport Surface Detection Equipment Model-X, 29 airports were selected for further analysis. Using taxi-out delay, traffic management initiative delay counts and commercial operation counts as metrics in a multiple-metric K-Means method, these airports were organized into three groups. San Jose International, Cleveland-Hopkins International and San Francisco International are recommended for development and testing of wheels-off time estimation methods as they are suitable representatives of these three groups. The second part of the paper is devoted to wheels-off time estimation using a simulation procedure that uses kinematic models of different types of aircraft and a node-link graph to simulate surface traffic. The central idea is to integrate the aircraft equations of motion along the path in the node-link graph while complying with separation constraints and rules for waiting to cross intersections and active runways. While the intent was to apply the wheels-off estimation method to San Jose, the geometry data and the surveillance data were not received in time for this study. Therefore, modeling, simulation and tests were done with Dallas-Fort Worth traffic for which the needed data were available. Of the two approaches described in the paper, the data-driven approach, which uses historical taxi-times, can be readily applied to airports like San Jose, Cleveland and San Francisco.