Wheezing illness caused by respiratory syncytial virus and other agents

Yasuno, Tomohiro; Shimizu, Takeshi; Maeda, Yosuke; Yamasaki, Atsuko; Amaya, Eriko; Kawakatsu, Hidekazu

doi:10.1111/j.1442-200x.2008.02702.x

Cited by 5 publications

(4 citation statements)

References 38 publications

(67 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The most common diagnosis in hMPV‐infected children was pneumonia. The clinical manifestations of hMPV and RSV infections are very similar, and range from mild respiratory problems to bronchiolitis and pneumonia; consequently, they are difficult to distinguish clinically …”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical and genetic features of human metapneumovirus infection in children

Park

Yun

Lim

et al. 2016

Pediatrics International

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

“…Many studies have reported the incidence, clinical features, and genetic variability of hMPV . hMPV mainly causes bronchiolitis and pneumonia in infants . The peak of incidence of hMPV is mainly in the spring in temperate latitudes .…”

mentioning

confidence: 99%

Clinical and genetic features of human metapneumovirus infection in children

Park

Yun

Lim

et al. 2016

Pediatrics International

View full text Add to dashboard Cite

show abstract

“…In contrast, studies that compare individuals with RSV LRTI to those with LRTI due to other respiratory pathogens (e.g. human rhinovirus and bocavirus) usually find no difference in the risk of subsequent RWEC/asthma [28,30,[61][62][63][64][65][66][67][68][69][70][71][72][73], or find RSV LRTI to be inversely associated with these outcomes compared to the non-RSV LRTI exposed [74][75][76][77][78][79][80][81][82][83]. Several studies compared the same exposure group (with RSV LRTI medical events) to both types of comparison groups and found a positive association between RSV LRTI and RWEC/asthma when comparing exposed individuals to those without LRTI, but no significant association when compared to those with a non-RSV LRTI [36,41,52,53,75,76,[84][85][86][87][88].…”

Section: Observational Studiesmentioning

confidence: 99%

Respiratory syncytial virus vaccine research and development: World Health Organization technological roadmap and preferred product characteristics

Vekemans

Moorthy

Giersing

et al. 2019

Vaccine

View full text Add to dashboard Cite

The respiratory syncytial virus causes a considerable respiratory disease burden globally, most markedly in young infants, in low and middle income countries. A diverse product pipeline illustrates the recent intensification of research and development activities for vaccines and monoclonal antibodies against RSV. With the aim to ensure that product development activities are directed to address the public health needs, the World Health Organization has developed a research and development technical roadmap and articulated product characteristics preferences.

show abstract

“…According to a birth cohort study, RSV was a risk factor for hospital admission with bronchiolitis. 5 However, its correlation to current wheezing remains uncertain at present. Respiratory viruses, such as human bocavirus (HBoV), human coronavirus (HCoV), and human metapneumovirus (hMPV), have been identified in children with lower RTIs, but its correlation to wheezing remains uncertain at present.…”

Section: Introductionmentioning

confidence: 99%

The relationship between rhinovirus infection and acute wheezing in young children with recurrent wheezing

et al. 2019

View full text Add to dashboard Cite

Asthma is a common chronic respiratory disease in childhood. The present study aims to assess the association between rhinovirus (RV) infection and acute wheezing in the occurrence of recurrent wheezing in 5-year old and younger children. A total of 109 children with recurrent wheezing and 70 children without wheezing (controls) were recruited from October 2013 to March 2015. Nasopharyngeal aspirate samples were obtained from all children. RV, human metapneumovirus (hMPV), and bocavirus (BoV) were tested by reverse transcription-polymerase chain reaction.Respiratory syncytial virus (RSV), parainfluenza virus (PIV), influenza virus (IV), and adenoviruses (ADV) were confirmed by detection of viral antigens via fluoroimmunoassay. Viral infection was more commonly detected in children with recurrent wheezing than in controls (odds ratio (OR): 6.10; 95% confidence interval (CI): 2.89-12.87). RV and RSV were found in both wheezing children and controls. However, RV was detected more in wheezing children than in controls (OR: 3.07; 95% CI: 1.37-6.90), followed by RSV (OR: 5.33; 95% CI: 1.53-18.62). Furthermore, RV more tended to infect wheezing children after infancy. Compared with children infected with other viruses, higher levels of eosinophil were found in wheezing children with RV infection (P < 0.05). RV was the main pathogen that induced exacerbation in young children with recurrent wheezing. Furthermore, the rate of RV infection was higher in children above 1 year old. RV infection might be associated with high levels of eosinophil.

show abstract

Wheezing illness caused by respiratory syncytial virus and other agents

Abstract: Wheezing illness in infancy caused by RSV is more common in younger infants, but it is not more severe than that caused by other pathogenic agents.

Cited by 5 publications

References 38 publications

Clinical and genetic features of human metapneumovirus infection in children

Clinical and genetic features of human metapneumovirus infection in children

Respiratory syncytial virus vaccine research and development: World Health Organization technological roadmap and preferred product characteristics

The relationship between rhinovirus infection and acute wheezing in young children with recurrent wheezing

Contact Info

Product

Resources

About