When Is There Nipple Involvement in Carcinoma of the Breast?

Parry, Richard G.; Cochran, Thomas C.; Wolfort, Francis G.

doi:10.1097/00006534-197704000-00010

Cited by 17 publications

(2 citation statements)

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“…Concern about the risks associated with nipple preservation is the main obstacle to acceptance of this approach. Many studies of pathological involvement of the nipple have been reported, with the incidence of nipple involvement by tumour ranging from 0 to 58 per cent ( Table 1 )23–40. If series with fewer than 100 patients are excluded, the range narrows to 5·6–31 per cent.…”

Section: Oncological Safetymentioning

confidence: 99%

Nipple-sparing mastectomy

Rusby

Smith

Gui

2010

British Journal of Surgery

171

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Background: Although effective local control is the primary goal of surgery for breast cancer, the longterm aesthetic outcome is also important. Nipple-sparing mastectomy aims to address this, but there is no consensus on its clinical application. Evidence relating to oncological safety, surgical technique and early data on aesthetic outcome was reviewed. Methods:The review was based on a PubMed search using the terms 'nipple-sparing' or 'subcutaneous mastectomy' and 'breast cancer'.Results: Large pathological studies report occult nipple involvement with cancer in 5·6-31 per cent, reflecting variation in inclusion criteria. Recent clinical series with careful patient selection report local recurrence in less than 5 per cent of patients. The incidence of cancer in the retained nipple after risk-reducing mastectomy is less than 1 per cent. Nipple necrosis rates range up to 8 and 16 per cent for total and partial necrosis respectively. Variations in outcome result from differences in extent of resection, placement of incisions and type of breast reconstruction.Conclusion: Nipple-sparing mastectomy is an acceptable technique for women undergoing risk-reducing mastectomy. In the therapeutic setting, it may be offered to patients with smaller tumours far from the nipple and favourable pathological features. Women should be counselled about nipple necrosis and the potential for local recurrence.

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Section: Oncological Safetymentioning

confidence: 99%

Nipple-sparing mastectomy

Rusby

Smith

Gui

2010

British Journal of Surgery

171

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“…Resection of the NAC has been rejected by many surgeons because of a purported higher incidence of multifocality and multicentricity associated with central breast cancers, both intraductal and invasive cancers. [1][2][3][4][5][6][7][8] In addition, many feel that resection of the NAC will lead to unacceptable cosmesis (historically, most often judged by the surgeon). 9 As a result of these concerns, women with central breast cancers were ineligible, and thus excluded from the large prospective randomized studies of breast-conserving surgery that definitively established breast conservation as an equivalent option (in terms of survival) in the 1980s and 1990s.…”

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confidence: 99%

Breast Conservation Surgery Using Nipple-Areolar Resection for Central Breast Cancers

Pezzi

Kukora²,

Audet³

et al. 2004

Arch Surg

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Hypothesis: Resection of the nipple-areolar complex (NAC) for central breast cancers that involve the nipple or areola, with postoperative radiation therapy, adheres to the oncologic principles established for breast conservation surgery of other breast cancers. Good or excellent cosmetic results can be achieved. The rate of ipsilateral breast recurrence will be similar to that seen with peripheral breast cancers. The indications for breast conservation surgery can be safely extended to include patients with breast cancers that involve the NAC.Design: Retrospective medical record review; follow-up patient questionnaire.Setting: Community teaching hospital.Patients: Fifteen patients, aged 46 to 88 years, whose central breast cancers involved the NAC precluding preservation of the NAC.

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Nipple-Sparing Mastectomy

Crowe¹

2004

Arch Surg

205

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When Is There Nipple Involvement in Carcinoma of the Breast?

Cited by 17 publications

References 0 publications

Nipple-sparing mastectomy

Nipple-sparing mastectomy

Breast Conservation Surgery Using Nipple-Areolar Resection for Central Breast Cancers

Nipple-Sparing Mastectomy

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