In this introduction to the Journal of Management Studies Special Issue on Meaningful Work, we explain the imperative for a deeper understanding of meaningfulness within the context of the current sociopolitical environment, coupled with the growing use of organizational strategies aimed at ‘managing the soul’. Meaningful work remains a contested topic that has been the subject of attention in a wide range of disciplines. The focus of this Special Issue is the advancement of theory and evidence about the nature, causes, consequences, and processes of meaningful work. We summarize the contributions of each of the seven articles that comprise the Special Issue and, in particular, note their methodological and theoretical plurality. In conclusion, we set forth a future research agenda based on five fundamental paradoxes of meaningful work.