When the course deviates from expected: Misplacement of an epicutaneo-caval catheter in a neonate

Kesman, Russell; Mehollin-Ray, Amy R.; Lantin-Hermoso, Regina; Colquitt, John L.; Fernandes, Caraciolo J.; Premkumar, Muralidhar H.

doi:10.1177/11297298211000871

Cited by 1 publication

(1 citation statement)

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“…Considering that the younger the gestational age and the lower the birth weight, the lower the autoimmunity and the worse the barrier function of skin and mucosa. [21] The greater the chance of CRBSI. Some scholars prospectively studied the risk factors of nosocomial infection in neonates in ICU, and the results showed that birth weight <1 kg was the largest risk factor of nosocomial infection in neonates.…”

Section: Discussionmentioning

confidence: 99%

Analysis and risk factors of deep vein catheterization-related bloodstream infections in neonates

Zhang,

Li,

et al. 2024

Medicine

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To investigate the incidence, risk factors, and pathogenic characteristics of catheter-related bloodstream infection caused by peripherally inserted central venous catheter in neonates, and to provide references for reducing the infection rate of peripherally inserted central venous catheter. The clinical data of 680 neonates who underwent peripherally inserted central catheter (PICC) in the neonatal intensive care unit from June 2020 to June 2023 were retrospectively analyzed. The risk factors and independent risk factors of catheter-related bloodstream infection caused by PICC were determined by univariate and multivariate analysis, respectively. Catheter-related bloodstream infection occurred in 38 of 680 neonates who underwent PICC. The infection rate was 4.74%. The proportions of fungi, gram-positive bacteria, and gram-negative bacteria were 42.11%, 36.84%, and 21.05%, respectively. Candida parapsilosis was the main fungus (18.42%), coagulase negative Staphylococcus was the main gram-positive bacteria (23.68%), and Klebsiella pneumoniae and Escherichia coli were the main gram-negative bacteria (7.89%). Univariate analysis showed that gestational age ≤32 weeks, birth weight ≤1500 g, congenital diseases, nutritional support, catheterization time, 5-minute APGAR score ≤7, and neonatal respiratory distress syndrome were associated with catheter-related bloodstream infection caused by PICC. Multivariate analysis showed that premature delivery, low birth weight, parenteral nutrition, long catheterization time, and 5-minute APGAR score ≤7 were associated with catheter-related bloodstream infection caused by PICC. Among the pathogens detected, there were 6 cases of K pneumoniae, 5 cases of coagulase negative staphylococci, and 2 cases of fungi. Low birth weight, premature delivery, off-site nutrition, long catheterization time, and 5-minute APGAR score ≤7 are independent risk factors for catheter-related bloodstream infection in neonates with peripherally inserted central venous catheters. The pathogenic bacteria are fungi and multidrug-resistant bacteria.

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Section: Discussionmentioning

confidence: 99%