When to Perform Urine Cultures in Respiratory Syncytial Virus–Positive Febrile Older Infants?

Kaluarachchi, Dinushan C.; Kaldas, V.; Erickson, Evelyn; Nunez, Randolph; Mendez, Magda D.

doi:10.1097/pec.0000000000000203

Cited by 8 publications

(8 citation statements)

References 12 publications

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“…One study was excluded owing to using the same cohort of patients for 2 articles. 23 Although corresponding authors with available contact information were emailed, no studies were able to provide additional UA data. Of the remaining 18 studies, 1-3,24-38 11 did not report UA data, leaving 7 for metaanalysis by reporting UA data and urine culture positivity (Tables 1 and 2).…”

Section: Resultsmentioning

confidence: 99%

“…After full-text review, 13 studies were further excluded, with the most frequent reason for exclusion being studies not reporting UTI prevalence (10 of 12) (Figure 1). One study was excluded owing to using the same cohort of patients for 2 articles . Although corresponding authors with available contact information were emailed, no studies were able to provide additional UA data.…”

Section: Resultsmentioning

confidence: 99%

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Association of Diagnostic Criteria With Urinary Tract Infection Prevalence in Bronchiolitis

et al. 2019

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IMPORTANCE Concomitant urinary tract infection (UTI) is a frequent concern in febrile infants with bronchiolitis, with a prior meta-analysis suggesting a prevalence of 3.3%. However, the definition of UTI in these studies has generally not incorporated urinalysis (UA) results. OBJECTIVE To conduct a systematic review and meta-analysis examining the prevalence of UTI in infants with bronchiolitis when positive UA results are incorporated into the UTI definition.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Association of Diagnostic Criteria With Urinary Tract Infection Prevalence in Bronchiolitis

et al. 2019

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“…In contrast, many studies are revealing a high prevalence rate, ranging from 4% to 8% [12][13][14][15][16][17]. Some even reported a rate of UTI of 10% or more [4,18].…”

Section: Discussionmentioning

confidence: 96%

“…The definition of a positive urine culture was not mentioned in some studies and was different across published studies [ 17 ]. For example, several studies used a positive culture of more than 10,000 CFUs of a single pathogen as their diagnostic criteria for UTI [ 10 , 11 , 16 ], while Kaluarachchi had three different criteria for UTI diagnosis: “the growth of a single known pathogen with colony counts meeting 1 of 3 criteria: (1) 1000 colony-forming units (CFU)/mL or greater for urine cultures obtained by suprapubic aspiration, (2) 50,000 CFUs/mL or greater from a catheterized specimen, or (3) 10,000 CFUs/mL or greater from a catheterized specimen in association with a positive urinalysis finding” [ 15 ].…”

Section: Discussionmentioning

confidence: 99%

Urinary Tract Infection in Children With Bronchiolitis: Is It Worth Testing Everyone?

Edun¹,

Aldibasi²,

Jamil³

2021

Cureus

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The current study aims to determine the prevalence of urinary tract infection (UTI) and the need to perform urine analysis and cultures in children admitted with bronchiolitis in a large tertiary children's hospital in Riyadh, Saudi Arabia. MethodsWe conducted a retrospective chart review of pediatric patients 0-2 years of age who were admitted with bronchiolitis from November 2016 till April 2017. All charts were analyzed to identify the children investigated for UTI, and their results were then reviewed. ResultsThere were 407 children admitted with bronchiolitis during the study period. Two-thirds of them were investigated for UTI. Only 2.6% of the patients tested positive for urine culture, and only 0.96% were found to have a true UTI. ConclusionThe prevalence of UTI in children with bronchiolitis is too low to justify routine screening. Therefore, only children with a high risk of having UTI should be investigated.

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“…In addition, it is not appropriate to predict UTI because it is common for patients with VI to show a fever for > 2 days. [15][16][17] Because we collected the data prospectively, we were able to collect data regarding the general condition of the patient and respiratory symptoms among family members from the guardian of the patient. As a result, there was no difference between the two groups in terms of the general condition of the patients as reported by the caregiver.…”

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confidence: 99%

A clinical prediction tool to predict urinary tract infection in pediatric febrile patients younger than 2 years old: a retrospective analysis of a fever registry

et al. 2021

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Objective Urinary tract infection (UTI) is a significant issue in young febrile patients due to potential long-term complications. Early detection of UTI is crucial in pediatric emergency departments (PEDs). We developed a tool to predict UTIs in children.Methods Clinical data of patients <24 months of age with a fever and UTI or viral infection were extracted from the fever registry collected in two PEDs. Stepwise multivariate logistic regression was performed to establish predictors of identified eligible clinical variables for the derivation of the prediction model.Results A total of 1,351 patients were included in the analysis, 643 patients from A hospital (derivation set) and 708 patients from B hospital (validation set). In the derivation set, there were more girls and a lower incidence of a past history of UTI, older age, less fever without source, and more family members with upper respiratory symptoms in the viral infection group. The stepwise regression analysis identified sex (uncircumcised male), age (≤12 months), a past history of UTI, and family members with upper respiratory symptoms as significant variables.Conclusion Young febrile patients in the PED were more likely to have UTIs if they were uncircumcised boys, were younger than 12 months of age, had a past history of UTIs, or did not have families with respiratory infections. This clinical prediction model may help determine whether to perform urinalysis in the PED.

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When to Perform Urine Cultures in Respiratory Syncytial Virus–Positive Febrile Older Infants?

Cited by 8 publications

References 12 publications

Association of Diagnostic Criteria With Urinary Tract Infection Prevalence in Bronchiolitis

Association of Diagnostic Criteria With Urinary Tract Infection Prevalence in Bronchiolitis

Urinary Tract Infection in Children With Bronchiolitis: Is It Worth Testing Everyone?

A clinical prediction tool to predict urinary tract infection in pediatric febrile patients younger than 2 years old: a retrospective analysis of a fever registry

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