Where Is Dopamine and how do Immune Cells See it?: Dopamine-Mediated Immune Cell Function in Health and Disease

Matt, Stephanie; Gaskill, Peter J.

doi:10.1007/s11481-019-09851-4

Cited by 201 publications

(207 citation statements)

References 588 publications

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“…So, one of the best strategies to support the immune system is to keep the mood in a good state. and some studies support the fact that dopamine is highly liked by the immune system [50,51].…”

Section: Musically Immune Stimulationmentioning

confidence: 79%

COVID-19 symphony: A review of possible music therapy effect in supporting the immune system of COVID-19 patient

Habib¹

2021

Highlights in BioScience

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Coronavirus, the current pandemic that takes lives of 1,936,632 until the time of the paper. Scientists over the world exhibited all efforts to fight the virus. Many supplements developed to fight coronavirus by supporting the immune system which is the strongest worrier against it for now. One of the neglected strategies to enhance immunity is music therapy. Music therapy can drive immunity into different conditions. Not only able to boost and suppress immunity but also many physiological and psychological diseases are treated with music therapy. It is more than just entertainment, and research shows that music therapy may be helpful and cost-effective to support standard therapy. This systemic review tries to explore the effect of music therapy and arrives at a conclusion suggesting routine procedures to support the patient with music therapy. However, the idea of using music therapy in improving the immune system must undergo clinical and medical confirmation to be used

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Section: Musically Immune Stimulationmentioning

confidence: 79%

COVID-19 symphony: A review of possible music therapy effect in supporting the immune system of COVID-19 patient

Habib¹

2021

Highlights in BioScience

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“…In addition, further studies on bias of immune responses toward inflammatory activity rather than adaptive immunity are warranted, together with further studies on associations of flightiness with immune competence (Hine et al, 2015(Hine et al, , 2019. The influence of dopamine release as a component of adrenergic tone on immune function also deserves attention (Matt and Gaskill, 2019;Broome et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

“…Adrenergic effects are mediated primarily by the catecholamines norepinephrine in the SNS and epinephrine in the AHS (Burdick et al, 2011b). The third catecholamine, dopamine, is also active in peripheral tissues, especially kidney, gut, and immune cells (Falck et al, 1964;Matt and Gaskill, 2019;Broome et al, 2020). Activity of the SNS and AHS pathways can differ both at rest and in response to specific types of stressor (Goldstein, 2003).…”

Section: Influence Of Adrenergic Pathways On Traits Associated With Fsmentioning

confidence: 99%

“…This divergence could lead to differences between the long-term effects of adrenergic tone and acute effects of adrenergic discharge during acute environmental challenge. Recent studies indicate that dopamine released from SNS within peripheral tissues is an important modulator of immune function (Matt and Gaskill, 2019;Broome et al, 2020) and therefore also deserves attention in studies on immune functions associated with FS. Activity of the parasympathetic nervous system also modulates immune function, for example, via the cholinergic anti-inflammatory reflex, thus providing an additional layer of autonomic nervous system modulation of immune responses (Kenney and Ganta, 2011), that furthermore can differ between individuals as illustrated by studies on coping styles (Koolhaas, 2008).…”

Section: Immune Functionmentioning

confidence: 99%

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Adrenergic Tone as an Intermediary in the Temperament Syndrome Associated With Flight Speed in Beef Cattle

Colditz

2021

Front. Anim. Sci.

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The temperament of farm animals can influence their resilience to everyday variations within the managed production environment and has been under strong direct and indirect selection during the course of domestication. A prominent objective measure used for assessing temperament in beef cattle is the behavioral flight response to release from confinement in a crush or chute. This behavioral measure, termed flight speed (also known as escape velocity) is associated with physiological processes including body temperature, feeding behavior, growth rate, carcass composition, immune function, and health outcomes. This review examines the functional links between this suite of traits and adrenergic activity of the sympathetic nervous system and the adrenomedullary hormonal system. It is suggested that flight speed is the behavioral aspect of an underlying “flightiness” temperament syndrome, and that elevated adrenergic tone in animals with a high level of flightiness (i.e., flighty animals) tunes physiological activities toward a sustained “fight or flight” defense profile that reduces productivity and the capacity to flourish within the production environment. Nonetheless, despite a common influence of adrenergic tone on this suite of traits, variation in each trait is also influenced by other regulatory pathways and by the capacity of tissues to respond to a range of modulators in addition to adrenergic stimuli. It is suggested that tuning by adrenergic tone is an example of homeorhetic regulation that can help account for the persistent expression of behavioral and somatic traits associated with the flight speed temperament syndrome across the life of the animal. At a population level, temperament may modulate ecological fit within and across generations in the face of environmental variability and change. Associations of flight speed with the psychological affective state of the animal, and implications for welfare are also considered. The review will help advance understanding of the developmental biology and physiological regulation of temperament syndromes.

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“…Dopamine (DA) is a very important catecholamine neurotransmitter, playing a central role in the regulation of the cardiovascular, nervous [30] and immune [31] systems, as well as in the renal [32] and pancreatic function [33], among other physiological processes. In blood and serum samples, DA concentration levels range from 1 nM up to 1 μM, while in urine DA levels range from 0.5 up to 2 μM [34].…”

Section: Introductionmentioning

confidence: 99%

Effect of Ionic Liquid Structure on the Electrochemical Response of Dopamine at Room Temperature Ionic Liquid‐modified Carbon Paste Electrodes (IL–CPE)

2020

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In this work 12 different ionic liquids (ILs) have been used added as co‐binders in the preparation of modified carbon paste electrodes (IL–CPEs) used for the voltammetric analysis of dopamine in Britton‐Robinson buffer. The ionic liquids studied were selected based on three main criteria: (1) increasing chain length of alkyl substituents (studying 1‐ethylimidazolium and ethyl, propyl, butyl, hexyl and decylmethylimidazolium bis(trifluoromethylsulfonyl)imide ionic liquids); (2) nature of the counter ion (dicyanamide, bis(trifluoromethylsulfonyl)imide and hexafluorophosphate) in 1‐butyl‐3‐methylimidazolium ionic liquids; and (3) cation ring structures (1‐butyl‐3‐methylimidazolium, 1‐butyl‐1‐methylpiperidinium, 1‐butyl‐1‐methylpyrrolidinium and 1‐butyl‐3‐methylpyridinium) in bis(trifluoromethylsulfonyl)imide or hexafluorophosphate (1‐butyl‐3‐methylimidazolium or 1‐butyl‐3‐methylpyridinium as cations) ionic liquids. The use of IL as co‐binders in IL–CPE results in a general enhancement of both the sensitivity and the reversibility of dopamine oxidation. In square wave voltammetry experiments, the peak current increased up to a 400 % when 1‐ethyl‐3‐methylimidazolium bis(trifluoromethylsulfonyl)imide was used as co‐binder, as compared to the response found with the unmodified CPE. Experimental data provide evidence that electrostatic and steric effects are the most important ones vis‐à‐vis these electrocatalytic effects on the anodic oxidation of dopamine on IL–CPE. The relative hydrophilicity of dicyanamide anions reduced the electrocatalytic effects of the corresponding ionic liquids, while the use of 1‐ethyl‐3‐methylimidazolium hexafluorophosphate or 1‐ethyl‐3‐methylimidazolium bis(trifluoromethylsulfonyl)imide (two relatively small and highly hydrophobic ionic liquids) as co‐binders in IL–CPE resulted in the highest electrocatalytic activity among all of the IL–CPE studied.

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Where Is Dopamine and how do Immune Cells See it?: Dopamine-Mediated Immune Cell Function in Health and Disease

Cited by 201 publications

References 588 publications

COVID-19 symphony: A review of possible music therapy effect in supporting the immune system of COVID-19 patient

COVID-19 symphony: A review of possible music therapy effect in supporting the immune system of COVID-19 patient

Adrenergic Tone as an Intermediary in the Temperament Syndrome Associated With Flight Speed in Beef Cattle

Effect of Ionic Liquid Structure on the Electrochemical Response of Dopamine at Room Temperature Ionic Liquid‐modified Carbon Paste Electrodes (IL–CPE)

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