Human capital has been acknowledged as a key driver for innovation, thereby promoting regional economic development in the knowledge era. University graduates from China’s “first-class” universities—the top 42 universities, included in the “double first-class” initiative, are considered highly educated human capital. Their migration patterns will exert profound impacts on regional development in China, however, little is known about the migration of these elite university graduates and its underlying driving forces. Using data from the 2018 Graduate Employment Reports, this study reveals that the uneven distribution of “first-class” universities and regional differentials largely shaped the migration of graduates from the university to work. Graduates were found aggregating in eastern first-tier cities, even though appealing talent-orientated policies aimed at attracting human capital had been launched in recent years by second-tier cities. Employing negative binomial models, this study investigates how the characteristics of the city of university and destinations affect the intensity of flows of graduates between them. The results showed that both jobs and urban amenities in the university city and destination city exert impacts on the inflow volume of graduates; whereas talent attraction policies introduced by many second-tier cities are found not to exert positive effects on attracting “first-class” university graduates presently. The trend of human capital migration worth a follow-up investigation, particularly given ongoing policy dynamics, and would shed light on the regional development disparities in China.