Which are the clinical consequences of Molar Incisor hypomineralization (MIH) in children and adolescents? Systematic review and meta-analysis

Gevert, Mayara Vitorino; Wambier, Letícia Maira; Ito, Larissa Yumi; Feltrin de Souza, Juliana; Chibinski, Ana Cláudia Rodrigues

doi:10.1007/s00784-024-05800-5

Clin Oral Invest

2024

DOI: 10.1007/s00784-024-05800-5

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Which are the clinical consequences of Molar Incisor hypomineralization (MIH) in children and adolescents? Systematic review and meta-analysis

Mayara Vitorino Gevert,

Letícia Maira Wambier,

Larissa Yumi Ito

et al.

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2024

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Cited by 4 publications

References 72 publications

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Molar Incisor Hypomineralization: Etiology, Correlation with Tooth Number Anomalies and Implications for Comprehensive Management Strategies in Children from Transylvania

Contac,

Pop,

Voidazan

et al. 2024

Diagnostics

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Background/Objectives: This study investigates the etiology of enamel developmental defects, specifically Molar Incisor Hypomineralization (MIH), and explores correlations between MIH and dental anomalies such as hypodontia to improve interdisciplinary restorative and orthodontic treatments. Additionally, it assesses the influence of stress factors on the development of enamel defects. Methods: Conducted from July to September 2024, this study involved 57 patients aged 6 to 11 from an urban setting, divided into two groups: 32 with MIH and 25 controls, selected based on criteria of mixed dentition without systemic pathology or chronic medication. Clinical evaluations, including intraoral photographs and panoramic radiographs, were performed alongside a detailed questionnaire addressed to the mothers covering prenatal, perinatal, and postnatal factors. Results: The average age of children with MIH was 7.5 years, in contrast to 7.04 years in the control group (p = 0.17). Significant differences were noted in maternal age, with MIH mothers older (35.56 years) than controls (29.36, p = 0.0001). The prevalence of MIH was higher in boys (66.7%) compared to girls (38.1%, p = 0.036). Factors such as prolonged labor, medication during birth, and early postnatal medication were significantly linked to MIH. The study shows a strong correlation with hypodontia, with a significantly higher incidence of tooth number anomalies (p = 0.009) in the study group. Conclusions: Overall, the study emphasizes the association of MIH with various maternal and birth-related factors and with hypodontia, highlighting the need for a comprehensive, multidisciplinary approach to diagnosis and treatment. Further research is recommended to investigate the relationship between stress factors and MIH.

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Molar Incisor Hypomineralization: Etiology, Correlation with Tooth Number Anomalies and Implications for Comprehensive Management Strategies in Children from Transylvania

Contac,

Pop,

Voidazan

et al. 2024

Diagnostics

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To Treat or to Extract Necrotic First Permanent Molars Between 8 and 12 Years of Age: A Retrospective Cohort Study

Vergier,

Berat,

Collignon

et al. 2024

JCM

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Background: First permanent molars (FPM) are highly susceptible to decay before the age of 15. When they are severely affected, the decision between conservation and extraction arises, particularly considering the potential for the second permanent molar (SPM) to replace the FPM. This cohort study aimed to evaluate clinical practices regarding FPM pulp necrosis treatment in children aged eight to twelve in two hospital departments in the Paris region. A second objective was to evaluate the one-year outcomes of the two therapies. Methods: A retrospective analysis was conducted using computerized billing software to identify patients aged eight to twelve who underwent either extraction or root canal treatment (RCT). Data collected included sex, age, arch involved, number of decayed surfaces, presence of Molar Incisor Hypomineralization (MIH), presence of infection, and treatment type. Results: A total of 66 patients were included, representing 61 extracted teeth and 23 RCT. Three main decision criteria were identified: presence of MIH (p < 0.005), extent of decay (p < 0.05), and SPM Nolla’s stage. A total of 48% of the patients were seen at one year. A total of 16 of the 32 extractions and five of the nine RCTs had favorable evolution (p = 1). Conclusions: The question of whether to perform RCT or extraction of necrotic FPM in children aged eight to twelve is difficult to assess. It appears that five criteria need to be considered before the decision: possibility of long-term sealed coronal reconstruction, SPM Nolla’s stage, follow-up possibilities, arch concerned, and presence of third permanent molar.

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Aesthetic protective coverage on molars with MIH: Case report

de Souza Peruch,

Barriviera,

Antunes Barriviera

et al. 2024

J Case Rep Images Dent

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Introduction: The management of molars affected with severe molar incisor hypomineralization (MIH) in young children has been one of the greatest challenges for the pediatric dentist. Determining the severity of the defect, behavior, patient acceptance, and parental expectations are determining factors in defining treatment strategies. Case Report: The objective of this case report is to demonstrate an aesthetic alternative for preventing fractures of severely affected MIH teeth, using a temporary protective covering. This coverage was carried out using composite resin and a semi-direct technique. The patient’s 9-month follow-up showed favorable adaptation and occlusion and satisfaction from the patient and parents, who placed aesthetics as the main factor for treatment decision. Conclusion: In this patient, the aesthetic factor was decisive for MIH treatment decision. It was performed an aesthetic protective coverage (APC) using an indirect composite technique.

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Which are the clinical consequences of Molar Incisor hypomineralization (MIH) in children and adolescents? Systematic review and meta-analysis

Cited by 4 publications

References 72 publications

Molar Incisor Hypomineralization: Etiology, Correlation with Tooth Number Anomalies and Implications for Comprehensive Management Strategies in Children from Transylvania

Molar Incisor Hypomineralization: Etiology, Correlation with Tooth Number Anomalies and Implications for Comprehensive Management Strategies in Children from Transylvania

To Treat or to Extract Necrotic First Permanent Molars Between 8 and 12 Years of Age: A Retrospective Cohort Study

Aesthetic protective coverage on molars with MIH: Case report

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