Which is better in patients with curatively resected extrahepatic biliary tract cancer? Adjuvant concurrent chemoradiation (CCRT) alone versus CCRT followed by maintenance chemotherapy

Lim, Kelvin; Oh, Do‐Youn; Chie, Eui Kyu; Jang, Jae Seong; Im, S. A.; Kim, T.; Kim, S.; Ha, Seung Yeon; Bang, Yung‐Jue

doi:10.1200/jco.2008.26.15_suppl.15659

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Cholangiocarcinomas1

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2009

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“…202 In another retrospective analysis of patients with extrahepatic cholangiocarcinoma, the addition of maintenance chemotherapy after adjuvant chemoradiation was found to have a survival benefit (i.e., 3-year overall survival of 75.6% with addition of maintenance chemotherapy vs. 34.8% with no maintenance chemo-therapy; P = .001). 203 These results provide support for recommending consideration of fluoropyrimidine chemoradiation followed by additional fluoropyrimi-dine or gemcitabine chemotherapy for patients with extrahepatic cholangiocarcinoma with either positive margins or positive regional lymph nodes (see page 365).…”

Section: Cholangiocarcinomasmentioning

confidence: 77%