White Fibrous Papulosis of the Neck

Zanca, Andrea; Contri, M. Baccarani; Carnevali, Caterina; Bertazzoni, Maria Grazia

doi:10.1111/j.1365-4362.1993.tb02818.x

Cited by 18 publications

(8 citation statements)

References 5 publications

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“…Patient age has ranged from 39 to 80 (mean, 62) years, suggesting that this disorder affects mostly middle-aged and elderly adults. [90][91][92] Etiology and pathogenesis. The pathogenesis of white fibrous papulosis of the neck is poorly understood, but it has been speculated that it is an intrinsic manifestation of aging.…”

Section: White Fibrous Papulosis Of the Neckmentioning

confidence: 99%

Acquired disorders of elastic tissue: Part II. decreased elastic tissue

Lewis

Bercovitch

Dill

et al. 2004

Journal of the American Academy of Dermatology

171

216

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Section: White Fibrous Papulosis Of the Neckmentioning

confidence: 99%

Acquired disorders of elastic tissue: Part II. decreased elastic tissue

Lewis

Bercovitch

Dill

et al. 2004

Journal of the American Academy of Dermatology

171

216

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“…The lesions are asymptomatic and gradually increase in number. There is some clinical resemblance to PXE, but as in PXE-PDE there are no systemic complications such as angioid streaks in fundo [59–62]. The etiology is unknown, but in view of its late onset in life, the condition may be the result of age-related changes in dermal collagen [63].…”

Section: Dermatological Diseases With (Near-) Identical Skin Lesionsmentioning

confidence: 99%

Histopathology of Pseudoxanthoma Elasticum and Related Disorders: Histological Hallmarks and Diagnostic Clues

2012

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Among ectopic mineralization disorders, pseudoxanthoma elasticum (PXE)—a rare genodermatosis associated with ocular and cardiovascular manifestations—is considered a paradigm disease. The symptoms of PXE are the result of mineralization and fragmentation of elastic fibers, the exact pathophysiology of which is incompletely understood. Though molecular analysis of the causal gene, ABCC6, has a high mutation uptake, a skin biopsy has until now been considered the golden standard to confirm the clinical diagnosis. Although the histological hallmarks of PXE are rather specific, several other diseases—particularly those affecting the skin—can present with clinical and/or histological characteristics identical to or highly resemblant of PXE. In this paper, we will summarize the histopathological features of PXE together with those of disorders that are most frequently considered in the differential diagnosis of PXE.

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“…at present, 32 Japanese patients, an Iranian [11], 2 Saudis [12] and 6 Europeans [13][14][15][16][17] have been reported. In the Japanese studies, 81% of the patients were male, while all of the other cases were female.…”

Section: White Fibrous Papulosis Of the Neckmentioning

confidence: 99%

Fibroelastolytic Patterns of Intrinsic Skin Aging: Pseudoxanthoma-elasticum-Like Papillary Dermal Elastolysis and White Fibrous Papulosis of the Neck

Rongioletti

Rebora²

1995

Dermatology

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Background: Cutaneous aging is due to intrinsic and extrinsic factors. While the pathologic hallmark of extrinsic aging (photoaging) is solar elastosis, intrinsic aging lacks any specific feature. Only a progressive thinning and loss of the dermal elastic network occasionally associated with focal thickening of the collagen bundles may be observed. In contrast to the different clinical patterns of solar elastosis, only one distinctive disorder has been related so far to intrinsic aging: the temporary wrinkles. Objective: Pseudoxanthoma-elasticum-like papillary dermal elastolysis (PDE) and white fibrous papulosis of the neck (WFP) are further clinicopathologic patterns of intrinsic aging. Material and Methods: Review of the literature and clinical and histologic studies of patients of our files. Results: PDE and WFP share some peculiar clinical and histologic features, namely their occurrence in late adulthood and thinning or loss of the elastic fibers, mainly in the papillary dermis. Moreover, elastolysis in PDE and focal fibrosis in WFP, along with the abnormal elastic fibers, immature elastogenesis and activation of fibroblasts observed in PDE, are quite similar to the changes described in intrinsic aging. Conclusions: PDE and WFP along with temporary wrinkles and some cases of noninflammatory middermal elastolysis could be classified as ‘age-related fibroelastolytic syndromes’.

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White Fibrous Papulosis of the Neck

Cited by 18 publications

References 5 publications

Acquired disorders of elastic tissue: Part II. decreased elastic tissue

Acquired disorders of elastic tissue: Part II. decreased elastic tissue

Histopathology of Pseudoxanthoma Elasticum and Related Disorders: Histological Hallmarks and Diagnostic Clues

Fibroelastolytic Patterns of Intrinsic Skin Aging: Pseudoxanthoma-elasticum-Like Papillary Dermal Elastolysis and White Fibrous Papulosis of the Neck

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