White Matter Correlates of Mild Traumatic Brain Injuries in Women Subjected to Intimate-Partner Violence: A Preliminary Study

Valera, Eve M.; Cao, Aihua; Pasternak, Ofer; Shenton, Martha E.; Kubicki, Marek; Makris, Nikos; Adra, Noor

doi:10.1089/neu.2018.5734

Cited by 72 publications

(76 citation statements)

References 45 publications

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“…To the authors knowledge there is no research on this topic in retired female athletes; however, there is limited evidence on the effect of repetitive, mostly mild, traumatic brain injuries in women subjected to intimate-partner violence. [65][66][67] Similar to our results, the authors found moderate correlations across studies between measures of learning/memory and brain injury scores (based on frequency and recency). Additionally, learning/memory performance and brain injury scores were associated with abnormalities on neuroimaging.…”

Section: Neurocognitive Performance and Cognitive Symptomssupporting

confidence: 89%

Neurocognitive performance and mental health of retired female football players compared to non-contact sport athletes

Prien

Feddermann-Demont

Verhagen

et al. 2020

BMJ Open Sport Exerc Med

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BackgroundAdverse long-term effects of playing football due to repetitive head impact exposure on neurocognition and mental health are controversial. To date, no studies have evaluated such effects in women.AimsTo (1) compare neurocognitive performance, cognitive symptoms and mental health in retired elite female football players (FB) with retired elite female non-contact sport athletes (CON), and to (2) assess whether findings are related to history of concussion and/or heading exposure in FB.MethodsNeurocognitive performance, mental health and cognitive symptoms were assessed using computerised tests (CNS-vital signs), paper pen tests (Category fluency, Trail-Making Test, Digit Span, Paced Auditory Serial Addition Test), questionnaires (Hospital Anxiety and Depression Scale, SF-36v2 Health Survey) and a symptom checklist. Heading exposure and concussion history were self-reported in an online survey and in a clinical interview, respectively. Linear regression was used to analyse the effect of football, concussion and heading exposure on outcomes adjusted for confounders.ResultsFB (n=66) performed similar to CON (n=45) on neurocognitive tests, except for significantly lower scores on verbal memory (mean difference (MD)=−7.038, 95% CI −12.98 to –0.08, p=0.038) and verbal fluency tests (MD=−7.534, 95% CI –13.75 to –0.46, p=0.016). Among FB weaker verbal fluency performance was significantly associated with ≥2 concussions (MD=−10.36, 95% CI –18.48 to –2.83, p=0.017), and weaker verbal memory performance with frequent heading (MD=−9.166, 95% CI –17.59 to –0.123, p=0.041). The depression score differed significantly between study populations, and was significantly associated with frequent heading but not with history of concussion in FB.ConclusionFurther studies should investigate the clinical relevance of our findings and whether the observed associations point to a causal link between repetitive head impacts and verbal memory/fluency or mental health.

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Section: Neurocognitive Performance and Cognitive Symptomssupporting

confidence: 89%

Neurocognitive performance and mental health of retired female football players compared to non-contact sport athletes

Prien

Feddermann-Demont

Verhagen

et al. 2020

BMJ Open Sport Exerc Med

View full text Add to dashboard Cite

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“…1,13,15,16 Moreover, a substantial percentage of women experience repetitive TBIs as a result of intimate partner violence. [17][18][19][20] Current scientific guidelines strongly advise considering sex and gender in analyzing and reporting outcomes and treatment effects. [21][22][23] Some studies have shown that women have less access and lower rates of direct transfers to trauma centers 6,24 and fewer admissions to intensive care 25 after traumatic injuries.…”

Section: Introductionmentioning

confidence: 99%

Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury

Mikolić

Klaveren

Groeniger

et al. 2020

Journal of Neurotrauma

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Traumatic brain injury (TBI) is a significant cause of disability, but little is known about sex and gender differences after TBI. We aimed to analyze the association between sex/gender, and the broad range of care pathways, treatment characteristics, and outcomes following mild and moderate/severe TBI. We performed mixed-effects regression analyses in the prospective multi-center Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) study, stratified for injury severity and age, and adjusted for baseline characteristics. Outcomes were various care pathway and treatment variables, and 6-month measures of functional outcome, health-related quality of life (HRQoL), post-concussion symptoms (PCS), and mental health symptoms. The study included 2862 adults (36% women) with mild (mTBI; Glasgow Coma Scale [GCS] score 13-15), and 1333 adults (26% women) with moderate/severe TBI (GCS score 3-12). Women were less likely to be admitted to the intensive care unit (ICU; odds ratios [OR] 0.6, 95% confidence interval [CI]: 0.4-0.8) following mTBI. Following moderate/severe TBI, women had a shorter median hospital stay (OR 0.7, 95% CI: 0.5-1.0). Following mTBI, women had poorer outcomes; lower Glasgow Outcome Scale Extended (GOSE; OR 1.4, 95% CI: 1.2-1.6), lower generic and disease-specific HRQoL, and more severe PCS, depression, and anxiety. Among them, women under age 45 and above age 65 years showed worse 6-month outcomes compared with men of the same age. Following moderate/severe TBI, there was no difference in GOSE (OR 0.9, 95% CI: 0.7-1.2), but women reported more severe PCS (OR 1.7, 95% CI: 1.1-2.6). Men and women differ in care pathways and outcomes following TBI. Women generally report worse 6-month outcomes, but the size of differences depend on TBI severity and age. Future studies should examine factors that explain these differences.

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“…As such, we, along with others, have chosen to include IPV-related strangulation injuries with TBI (Campbell et al, 2018;Kwako et al, 2011;St. Ivany & Schminkey, 2016;Valera et al, 2018).…”

Section: Introductionmentioning

confidence: 99%

Traumatic brain injury and intimate partner violence: Addressing knowledge and service gaps among indigenous populations in Canada

et al. 2019

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BackgroundTraumatic brain injury (TBI) is a serious consequence of intimate partner violence (IPV) that is often overlooked. In the case of Indigenous women in Canada the challenges are broad, multidimensional, and left almost entirely unexplored. Given the elevated rates of violence and injury experienced by women exposed to IPV and the increased levels of physical assault among Indigenous women in Canada, it is important to understand the unique experiences and service needs of these women. This study sought to identify barriers and facilitating factors for TBI-sensitive service provision for Indigenous women experiencing IPV.Method:As part of a larger national stakeholder consultation process to develop a TBI educational toolkit for IPV service providers, input from Indigenous stakeholders was specifically sought to allow for insights into unique challenges and strengths related to this population. Interviews and focus groups were conducted with IPV direct-service providers, support professionals, and advocates working with Canadian First Nations and Inuit women.Findings:Findings suggest that multiple intersections of marginalization, shame and stigma, and colonization, coupled with significant barriers to service provision in remote communities are such that solutions generated for urban-based settler populations are ineffective.Conclusions:Recommendations include a widespread educational campaign to raise awareness of the seriousness of TBI among Indigenous women exposed to IPV. Education is particularly important among healthcare and direct service providers, survivors and their families and communities, legal professionals and child protection agencies, and Indigenous and settler government bodies. Future research should focus on expanding our understanding of this complex issue and developing culturally sensitive, community-based supports.

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White Matter Correlates of Mild Traumatic Brain Injuries in Women Subjected to Intimate-Partner Violence: A Preliminary Study

Cited by 72 publications

References 45 publications

Neurocognitive performance and mental health of retired female football players compared to non-contact sport athletes

Neurocognitive performance and mental health of retired female football players compared to non-contact sport athletes

Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury

Traumatic brain injury and intimate partner violence: Addressing knowledge and service gaps among indigenous populations in Canada

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