White sponge nevus of the oral cavity: Affecting members of two generations in a family

Abstract

The typical feature is the autosomal dominant heritance and clinically dormant, non-scarpalble, white diffuse, soft, thickened white plaques with a corrugated surface affecting mostly the buccal mucosa bilaterally which can substantially lead to the diagnosis of white sponge nevus. K E Y W O R D Sautosomal dominant, Cannon's disease, oral mucosa, white lesion, white sponge nevus How to cite this article: Gupta A, Lamichhane RS, Redhu A. White sponge nevus of the oral cavity: Affecting members of two generations in a family.

Familiar white sponge nevus

“…A histopathological analysis may be performed purely to corroborate the initial diagnosis. 6 The main histological findings include the presence of acanthosis with intercellular edema and vacuolization, as well as parakeratotic or orthokeratotic hyperkeratosis in the superficial layers. This entity may resemble a wide spectrum of oral disorders that may present as diffuse white plaques.…”