2008
DOI: 10.2215/cjn.03540807
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White Thrombus Formation in Blood Tubing Lines in a Chronic Hemodialysis Unit

Abstract: Background and objectives: Previous reports have described white particulate matter in banked blood components, but no prior public reports describe such matter in blood tubing during the course of routine in-center hemodialysis. This report describes the events, investigations, and preliminary conclusions associated with the spontaneous formation of adherent white thrombus in the venous and arterial blood lines during routine in-center hemodialysis treatments.Design

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Cited by 7 publications
(10 citation statements)
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“…AV fistula are preferred over hemodialysis catheters due to the complications associated with catheter use, which include a high incidence of thrombosis, 20,21 and bacterial infections. 22 Furthermore, hemodialysis catheter dysfunction is associated with significant mortality.…”
Section: Discussionmentioning
confidence: 99%
“…AV fistula are preferred over hemodialysis catheters due to the complications associated with catheter use, which include a high incidence of thrombosis, 20,21 and bacterial infections. 22 Furthermore, hemodialysis catheter dysfunction is associated with significant mortality.…”
Section: Discussionmentioning
confidence: 99%
“…Similar material has been described in banked blood components, hemodialysis tubing, hematopoietic stem cell collection lines, and in the LDL‐apheresis buffy coat, but this has not been described in TPE circuitry 1‐4 . The presence of PLTs and interspersed lymphocytes combined with the absence of fibrin suggest that the material's formation occurred secondary to the centrifugal layering of blood elements and procedural inefficiency.…”
mentioning
confidence: 65%
“…Similar material has been described in banked blood components, hemodialysis tubing, hematopoietic stem cell collection lines, and in the LDL-apheresis buffy coat, but this has not been described in TPE circuitry. [1][2][3][4] The presence of PLTs and interspersed lymphocytes combined with the absence of fibrin suggest that the material's formation occurred secondary to the centrifugal layering of blood elements and procedural inefficiency. In banked components, similar material, referred to as "white particulate matter," is thought to result from centrifugal conditions and is composed of PLTs, white blood cells, fibrin, and cellular debris.…”
mentioning
confidence: 99%
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“…3 There is also a high incidence of thrombosis with the use of dialysis catheters. [4][5][6] These values indicate the need for further improvement in the development and optimal design of dialysis catheters.…”
mentioning
confidence: 99%