Moving beyond the guidelines to improve detection of viral hepatitis and linkage to care Hepatitis B virus (HBV) infection complicates the care of people with HIV (PWH) [1], particularly in endemic regions like sub-Saharan Africa, where nearly two million individuals live with HIV/HBV coinfection [2]. Hepatitis B surface antigen (HBsAg) can go undetected in PWH [3] in limited-resource settings, leaving patients vulnerable to liver disease, including cirrhosis, hepatocellular carcinoma, and liver failure. In the United States, the Centers for Disease Control and Prevention (CDC) has updated HBV screening guidelines in early 2023, recommending universal screening rather than risk-based testing [4].However, making a dent in the public health burden of HBV infection for PWH and the population at large may require creative solutions that go beyond the guidelines.