WHOCARES: data-driven WHOle-brain CArdiac signal REgression from highly accelerated simultaneous multi-Slice fMRI acquisitions

Abstract

Cardiac pulsation is a physiological confound of functional magnetic resonance imaging (fMRI) time-series that introduces spurious signal fluctuations in proximity to blood vessels. fMRI alone is not sufficiently fast to resolve cardiac pulsation. Depending on the ratio between the instantaneous heartrate and the acquisition sampling frequency ( 1