Whole-body MR imaging in psoriatic arthritis: Additional value for therapeutic decision making

Weckbach, Sabine; Schewe, Stefan; Michaely, Henrik J.; Steffinger, Denise; Reiser, Maximilian; Gläser, Christian

doi:10.1016/j.ejrad.2009.06.020

Cited by 86 publications

(52 citation statements)

References 38 publications

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“…However, the significance of reduction in bone edema in PsA needs to be determined in larger cohort studies. Whole-body MRI imaging was shown to be well-tolerated, superior to clinical evaluation, and helpful in therapeutic decision making in a recent study from Germany [49]. Bone scintigraphy was shown to detect subclinical joint involvement in patients with psoriasis [50].…”

Section: Imaging Biomarkersmentioning

confidence: 97%

Update on Biomarkers in Psoriatic Arthritis

Chandran

Gladman

2010

Curr Rheumatol Rep

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Biomarkers in psoriatic arthritis (PsA) may serve as surrogate end points for disease outcome and can provide insights into disease susceptibility and natural history. Biomarkers could relate to diagnosis, pathogenesis, prognosis, therapeutic response, and comorbidities. The "felt need" is, however, in the development of biomarkers for the presence of PsA in patients with psoriasis, as well as that for joint damage. During the past few years, many studies related to PsA biomarkers have been conducted. These studies are reviewed here. C-reactive protein, matrix metalloproteinase-3, and circulating osteoclast precursors show promise. An international goal-directed study to determine biomarkers for joint damage in PsA is now under way through a collaborative effort of GRAPPA (the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis) and OMERACT (Outcome Measures for Rheumatology Clinical Trials).

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Section: Imaging Biomarkersmentioning

confidence: 97%

Update on Biomarkers in Psoriatic Arthritis

Chandran

Gladman

2010

Curr Rheumatol Rep

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“…108 In a proof-of-concept study testing whether whole-body MRI is feasible, the scans were well-tolerated by PsA patients, and the most often detected pathology was enthesitis. 109 Recently, 7 clinical enthesitis indices were examined by whole-body MRI in patients with PsA, axial SpA and healthy subjects and compared with entheseal tenderness. 110 A moderate agreement between MRI enthesitis and clinical examination was found, suggesting a role for whole-body MRI in detecting subclinical inflammation.…”

Section: New Mri Methodsmentioning

confidence: 99%

Imaging in Psoriatic Arthritis

Poggenborg

Østergaard

2015

Rheumatic Disease Clinics of North America

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“…Dynamic contrast-enhanced MR imaging has been purported to play a role in the differentiation of RA and psoriatic arthritis in the hand or wrist based on differences in synovial enhancement (105). Whole-body MR imaging has been shown to enable assessment of more global disease extent and activity with reasonable imaging time and consequently good patient acceptance (106). Another interesting new diagnostic technique is fluorescence optical imaging, which is highly sensitive in the detection of inflammatory processes in the hands (96).…”

Section: Psoriatic Arthritismentioning

confidence: 99%

The Role ofRadiologyin the Evolution of the Understanding of Articular Disease

Huang

Schweitzer²

2014

Radiology

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Both the clinical practice of radiology and the journal Radiology have had an enormous effect on our understanding of articular disease. Early descriptions of osteoarthritis (OA) appeared in Radiology. More recently, advanced physiologic magnetic resonance (MR) techniques have furthered our understanding of the early prestructural changes in patients with OA. Sodium imaging, delayed gadolinium-enhanced MR imaging of cartilage, and spin-lattice relaxation in the rotating frame (or T1ρ) sequences have advanced understanding of the pathophysiology and pathoanatomy of OA. Many pioneering articles on rheumatoid arthritis (RA) also have been published in Radiology. In the intervening decades, our understanding of the natural history of RA has been altered by these articles. Many of the first descriptions of crystalline arthropathies, including gout, calcium pyrophosphate deposition, and hydroxyapatite deposition disease, appeared in Radiology.

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Whole-body MR imaging in psoriatic arthritis: Additional value for therapeutic decision making

Cited by 86 publications

References 38 publications

Update on Biomarkers in Psoriatic Arthritis

Update on Biomarkers in Psoriatic Arthritis

Imaging in Psoriatic Arthritis

The Role ofRadiologyin the Evolution of the Understanding of Articular Disease

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