Whole-Body MR Imaging in the German National Cohort: Rationale, Design, and Technical Background

Bamberg, Fabian; Kauczor, Hans‐Ulrich; Weckbach, Sabine; Schlett, Christopher L.; Forsting, Michael; Ladd, Susanne C.; Greiser, Karin Halina; Weber, Marc‐André; Schulz‐Menger, Jeanette; Niendorf, Thoralf; Pischon, Tobias; Caspers, Svenja; Amunts, Katrin; Berger, Klaus; Bülow, Robin; Hosten, Norbert; Hegenscheid, Katrin; Kröncke, Thomas; Linseisen, Jakob; Günther, Matthias; Hirsch, Jochen G.; Köhn, Alexander; Hendel, Thomas; Wichmann, Heinz‐Erich; Schmidt, Börge; Jöckel, Karl‐Heinz; Hoffmann, W. H.; Kaaks, Rudolf; Reiser, Maximilian; Völzke, Henry

doi:10.1148/radiol.2015142272

Cited by 152 publications

(127 citation statements)

References 54 publications

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“…Therefore, we may assume that the rate of fatty liver diseases as an expression of obesity is likely similar throughout Germany. In the near future, we will be able to confirm this assumption by using data from the largest population-based study in Germany, the National Cohort, which will investigate the rate of fatty liver, among other pathologic conditions, in various German states (38). …”

Section: Discussionmentioning

confidence: 91%

Prevalence of Fatty Liver Disease and Hepatic Iron Overload in a Northeastern German Population by Using Quantitative MR Imaging

et al. 2017

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Section: Discussionmentioning

confidence: 91%

Prevalence of Fatty Liver Disease and Hepatic Iron Overload in a Northeastern German Population by Using Quantitative MR Imaging

et al. 2017

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“…Use of WB-MRI for screening in healthy asymptomatic subjects has also been reported [5–14]. The main use of MRI for screening is for malignant tumors and atherosclerosis.…”

Section: Discussionmentioning

confidence: 99%

“…In the recent years, with the developments in magnetic resonance imaging (MRI) technology, another field of diagnostic imaging, which is screening in asymptomatic subjects, i.e. check-up examination, has been introduced [5–14]. The multiplanar imaging, high spatial resolution, anatomical and functional imaging capabilities make MRI an alternative for computed tomography (CT) in screening [15].…”

Section: Introductionmentioning

confidence: 99%

Whole-Body MRI Screening in Asymptomatic Subjects; Preliminary Experience and Long-Term Follow-Up Findings

et al. 2016

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SummaryBackgroundThe aim of this study is to describe the technique and to evaluate the results of whole-body magnetic resonance imaging in an asymptomatic population.Material/MethodsBetween March 2009 and December 2011, 118 consecutive subjects undergoing thorough medical check-up were prospectively included in the study. MRI was performed with a 205-cm moving table, parallel imaging and automatic image composing software.ResultsIn 83 subjects (70%), 103 benign lesions were detected. Two malignant (adrenal and renal carcinoma) lesions and one precancerous (pancreatic mucinous carcinoma) lesion were detected. The most common lesions were renal cysts, liver hemangiomas, liver cysts, thyroid nodules, and uterine leiomyomas.ConclusionsWB-MRI is able to cover area from head to toes in one diagnostic work-up, and besides the anatomic regions evaluated by conventional radiological modalities, i.e. brain parenchyma, bones and extremities, can be evaluated in one examination.

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“…X-ray or CT involve ionizing radiation and are thus potentially harmful, representing an ethical problem in case of healthy volunteers. For the same reason, MRI is used without a contrast agent [BKWea15].…”

Section: Population-based Cohort Study Datamentioning

confidence: 99%

A Survey of Visual Analytics for Public Health

Preim

Lawonn²

2019

Computer Graphics Forum

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We describe visual analytics solutions aiming to support public health professionals, and thus, preventive measures. Prevention aims at advocating behaviour and policy changes likely to improve human health. Public health strives to limit the outbreak of acute diseases as well as the reduction of chronic diseases and injuries. For this purpose, data are collected to identify trends in human health, to derive hypotheses, e.g. related to risk factors, and to get insights in the data and the underlying phenomena. Most public health data have a temporal character. Moreover, the spatial character, e.g. spatial clustering of diseases, needs to be considered for decision‐making. Visual analytics techniques involve (subspace) clustering, interaction techniques to identify relevant subpopulations, e.g. being particularly vulnerable to diseases, imputation of missing values, visual queries as well as visualization and interaction techniques for spatio‐temporal data. We describe requirements, tasks and visual analytics techniques that are widely used in public health before going into detail with respect to applications. These include outbreak surveillance and epidemiology research, e.g. cancer epidemiology. We classify the solutions based on the visual analytics techniques employed. We also discuss gaps in the current state of the art and resulting research opportunities in a research agenda to advance visual analytics support in public health.

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Whole-Body MR Imaging in the German National Cohort: Rationale, Design, and Technical Background

Cited by 152 publications

References 54 publications

Prevalence of Fatty Liver Disease and Hepatic Iron Overload in a Northeastern German Population by Using Quantitative MR Imaging

Prevalence of Fatty Liver Disease and Hepatic Iron Overload in a Northeastern German Population by Using Quantitative MR Imaging

Whole-Body MRI Screening in Asymptomatic Subjects; Preliminary Experience and Long-Term Follow-Up Findings

A Survey of Visual Analytics for Public Health

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