Whole-body MRI added to gadoxetic acid-enhanced liver MRI for detection of extrahepatic disease in patients considered eligible for hepatic resection and/or local ablation of colorectal cancer liver metastases

Sivesgaard, Kim; Larsen, Lars; Sørensen, Michael; Kramer, Stine; Schlander, Sven; Amanavicius, Nerijus; Mortensen, Frank Viborg; Pedersen, Erik Morre

doi:10.1177/0284185119855184

Cited by 4 publications

(2 citation statements)

References 34 publications

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“…The b-value was high enough to suppress ow from pulmonary veins while obtaining a high SNR. A similar approach has previously been useful in detecting lung metastases in colon cancer (Sivesgaard et al 2020).…”

Section: Discussionmentioning

confidence: 95%

Can whole-body MRI replace CT in management of metastatic testicular cancer? A prospective, non-inferiority study

Larsen

Løgager

Bylov

et al. 2022

J Cancer Res Clin Oncol

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Purpose Concerns of imaging-related radiation in young patients with high survival rates have increased the use of magnetic resonance imaging (MRI) in testicular cancer (TC) stage I. However, computed tomography (CT) is still preferred for metastatic TC.The purpose of this study was to compare whole-body MRI incl. diffusion-weighted whole-body imaging with background body signal suppression (DWIBS) with contrast-enhanced, thoracoabdominal CT in metastatic TC.Methods A prospective, non-inferiority study of 84 consecutive patients (median age 33 years) with newly diagnosed metastatic TC (February 2018 -January 2021). Exclusion criteria were age <18 years, claustrophobia and MRI contraindications. Patients had both MRI and CT before and after treatment. Anonymised images were reviewed by experienced radiologists.Lesion malignancy was evaluated on a Likert scale (1 benign -4 malignant). Sensitivity, speci city, positive predictive value, negative predictive value and accuracy were calculated on patient and lesion level. For non-inferiority testing, the difference in sensitivity between CT and MRI was calculated. The level of signi cance was set at 5%. ROC curves and interobserver agreement were calculated.Results On patient level, MRI had 98% sensitivity and 75% speci city compared to CT. On lesion level within each modality, MRI had 99% sensitivity and 78% speci city, whereas CT had 98% sensitivity and 88% speci city. MRI sensitivity was non-inferior to CT (difference 0.57% (95% CI -1.4-2.5%)). The interobserver agreement was substantial between CT and MRI.Conclusion MRI with DWIBS was non-inferior to contrast-enhanced CT in detecting metastatic TC disease.Trial registration www.clinicaltrials.gov NCT03436901, nished July 1 st 2021.

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Section: Discussionmentioning

confidence: 95%

Can whole-body MRI replace CT in management of metastatic testicular cancer? A prospective, non-inferiority study

Larsen

Løgager

Bylov

et al. 2022

J Cancer Res Clin Oncol

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“…It can not only obtain detailed diagnostic images of human organs and tissues but also detect the chemical components and reactions of living organs and tissues. It is featured with clear images, high resolution, various parameters, and good soft tissue display [ 7 , 8 ]. With the continuous development of technology in the medical field, high-end MRI technology based on conventional MRI has gradually been applied to the liver.…”

Section: Introductionmentioning

confidence: 99%

Firework Optimization Algorithm-Based Diagnosis of Hepatocellular Carcinoma and Hepatic Cavernous Hemangioma Using MRI Images

Chen

Fang

et al. 2021

Contrast Media & Molecular Imaging

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This study was aimed to explore the diagnostic features of magnetic resonance imaging (MRI) on hepatocellular carcinoma (HCC) and hepatic cavernous hemangioma (HCH). A fireworks algorithm optimization (FAO) was proposed based on the fireworks algorithm (FA), and it was compared with the maximum between-class variance method (OTSU) and the maximum entropy threshold method (KSW) for analysis. In addition, it was applied to the diagnosis of MRI images of 55 HCC patients in the experimental group (group E) and 55 HCH patients in the control group (group C). It was found that the FAO showed a greatly lower difference function (DF) and a shorter running time in contrast to the OTSU and KSW algorithms ( P < 0.05 ); the diagnostic accuracy (DA) of the T1-weighted image (T1WI) for patients in groups E and C was 85.31% and 95.85%, respectively, and the DA of the T2-weighted image (T2WI) was 97.84% (group E) and 89.71% (group C), respectively. In short, FAO showed an excellent performance in segmentation and reconstruction of MRI images for liver tissue, and T1WI and T2WI of MRI images showed high accuracy in diagnosing the HCC and HCH, respectively.

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CSM-Net: A Multi-Task Colorectal Cancer Analysis Framework

Sui

Zhang

et al. 2020

Sens Imaging

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Whole-body MRI added to gadoxetic acid-enhanced liver MRI for detection of extrahepatic disease in patients considered eligible for hepatic resection and/or local ablation of colorectal cancer liver metastases

Cited by 4 publications

References 34 publications

Can whole-body MRI replace CT in management of metastatic testicular cancer? A prospective, non-inferiority study

Can whole-body MRI replace CT in management of metastatic testicular cancer? A prospective, non-inferiority study

Firework Optimization Algorithm-Based Diagnosis of Hepatocellular Carcinoma and Hepatic Cavernous Hemangioma Using MRI Images

CSM-Net: A Multi-Task Colorectal Cancer Analysis Framework

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