Whole-body MRI in the detection of bone marrow infiltration in patients with plasma cell neoplasms in comparison to the radiological skeletal survey

Ghanem, Nadir; Lohrmann, Christian; Engelhardt, Monika; Pache, Gregor; Uhl, Markus; Saueressig, Ulrich; Kotter, Elmar; Langer, Mathias

doi:10.1016/j.clinimag.2006.08.018

Cited by 39 publications

(43 citation statements)

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“…A solution in which the active slice package can be moved towards the feet is possible but has not been implemented yet. However, this is only a minor drawback in multiple myeloma imaging as the affliction of distal extremities is extremely rare [5,11].…”

Section: Discussionmentioning

confidence: 97%

“…Whole-body MRI was not compared to radiological skeletal survey [11,32], whole-body multidetector CT [8] or PET [9] for imaging of multiple myeloma until 2006, and it showed significantly higher detection rates of plasma cell infiltration. WB MRI and MRI of the spine are considered to be the imaging techniques of choice for multiple myeloma [33].…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, the assessment of curvilinear structures such as the scapula or ribs might be difficult using a standard coronal WB protocol [11].…”

Section: Introductionmentioning

confidence: 99%

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Comparison of a new whole-body continuous-table-movement protocol versus a standard whole-body MR protocol for the assessment of multiple myeloma

et al. 2010

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

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Comparison of a new whole-body continuous-table-movement protocol versus a standard whole-body MR protocol for the assessment of multiple myeloma

et al. 2010

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“…Abb. 4; [13]). In einer Vergleichsuntersuchung an 100 Patienten mit monoklonalen Plasmazellerkrankungen wiesen Bäuerle et al [1] nach, dass bei 10% der Patienten ausschließlich Verän-derungen außerhalb des Achsenskeletts nachweisbar sind, die bei einem axialen MRT übersehen würden.…”

Section: Magnetresonanztomographieunclassified

Multiples Myelom: Aktuelle Empfehlungen für die Bildgebung

Hillengaß

Delorme

2012

Radiologe

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For the initial diagnosis of monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma or symptomatic multiple myeloma, a whole-body MRI and a whole body low-dose CT should be performed. For MGUS and asymptomatic myeloma, whole body MRI only should be performed for follow-up until detection of first bone destruction. Patients with symptomatic multiple myeloma and known bone destruction will usually have whole body low-dose CT, supplemented by MRI studies where clinically required.

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“…With the development of MR machines that offer the capability to examine large regions of the body without patient and/or coil repositioning [1], MRI can now be used for imaging systemic aspects of diseases, e.g., in oncology [1][2][3][4][5][6]. But documentation of complex pathologies requires a fast and easy assessment of all findings.…”

Section: Introductionmentioning

confidence: 99%

Image quality improvement of composed whole-spine MR images by applying a modified homomorphic filter—first results in cases of multiple myeloma

et al. 2008

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To establish a modified homomorphic filter (BiFiC) for post-processing of composed MR images in clinical routine and to evaluate it in special regards to image quality and diagnostic safety. Twenty-three whole-spine examinations were post-processed with the filter. Qualitative image evaluation included documentation of lesions and their visualization at original and post-processed images. Variations of signal intensities were calculated pixel by pixel and visualized by color-coded maps. Quantitative data evaluation was conducted by region-by-region analysis with standardized regions of interests. The BiFiC filter could be implemented successfully on the scanner's software platform and used within clinical routine. Color-coded maps could demonstrate that the BiFiC filter improves the signal uniformity in all cases, including images with metallic artifacts caused by implants. The subjective image quality of the post-processed images was improved in 22 out of the 23 MR examinations; in one case it was rated as equal. All pathologies were visualized on post-processed images without the need of additional contrast adjustments. The implemented BiFiC filter significantly improves image signal homogeneity. The algorithm can consequently be integrated into clinical routine as an automatic image post-processing step.

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Whole-body MRI in the detection of bone marrow infiltration in patients with plasma cell neoplasms in comparison to the radiological skeletal survey

Cited by 39 publications

References 0 publications

Comparison of a new whole-body continuous-table-movement protocol versus a standard whole-body MR protocol for the assessment of multiple myeloma

Comparison of a new whole-body continuous-table-movement protocol versus a standard whole-body MR protocol for the assessment of multiple myeloma

Multiples Myelom: Aktuelle Empfehlungen für die Bildgebung

Image quality improvement of composed whole-spine MR images by applying a modified homomorphic filter—first results in cases of multiple myeloma

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