2023
DOI: 10.1101/2023.11.16.567365
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Whole-body positive synchronization pattern of metabolic transcriptomes

Ehud Z. Sussman,
Dana Mor,
Judith Somekh

Abstract: Understanding the relationship between transcriptomes in the entire body is crucial for comprehending health and disease. To achieve this, we have developed a framework that allows us to measure the general coordination pattern of functionally similar transcriptomes at a whole-body scale. Our approach employs meta-network level analysis to determine the interconnectivity level of metabolic co-expression modules throughout the body as opposed to randomly selected modules. We utilize dimensionality reduction of … Show more

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