Whole-Body Vibration Exercise Improves Functional Parameters in Patients With Osteogenesis Imperfecta: A Systematic Review With a Suitable Approach

Abstract

Background: Patients with osteogenesis imperfecta (OI) have abnormal bone modelling and resorption. The bone tissue adaptation and responsivity to dynamic and mechanical loading may be of therapeutic use under controlled circumstances. Improvements due to the wholebody vibration (WBV) exercises have been reported in strength, motion, gait, balance, posture and bone density in several osteopenic individuals, as in post-menopausal women or children with disabling conditions, as patients with OI. The aim of this investigation was to systematically analyse the current available literature to determine the effect of WBV exercises on functional parameters of OI patients. Materials and methods: Three reviewers independently accessed bibliographical databases. Searches were performed in the PubMed, Scopus, Science Direct and PEDro databases using keywords related to possible interventions (including WBV) used in the management of patients with osteogenesis imperfecta. Results: Three eligible studies were identified by searches in the analysed databases. Conclusion: It was concluded that WBV exercises could be an important option in the management of OI patients improving the mobility and functional parameters. However, further studies are necessary for establishing suitable protocols for these patients.

Musculoskeletal Outcomes from Chronic High-Speed, High-Impulse Resistance Exercise

“…Unlike resistance exercise, BMD results from mechanical loading stimuli that did not impart sufficient magnitudes of force also yielded fewer gains than our calcaneal results [1,21,28,44,54]. They include chronic interventions in which subjects received whole body vibration [21,44] or wore an accelerometer as they performed high-speed activity [1,28,54].…”

“…In contrast various exercise/therapeutic modalities were examined for their impact on BMC and BMD, but many appear to lack at least one mechanical loading feature. For instance, chronic high-speed activity and whole body vibration do not impart sufficient magnitudes of force, which may limit bone growth [1,21,28,44]. Conversely, the rate and frequency of mechanical stimuli is compromised by heavy loads used with resistive exercise [15,16,58].…”

“…They include chronic interventions in which subjects received whole body vibration [21,44] or wore an accelerometer as they performed high-speed activity [1,28,54]. Whole body vibration's impact on BMD is unclear and likely the result of multiple factors [21,44]. In contrast impact loading from high-speed physical activity yielded small ( + 1.1-1.9 %) but significant BMD gains [28].…”

Osteogenesis imperfecta and physical therapy: A review of recent trends during the COVID-19 pandemic

“…Depending on the position of the patient's feet on the platform, the amplitude of the vibration will vary from 0 mm at the axis of the platform to 1 cm at the edge. (Högler et al, 2017;Sa-Caputo et al, 2017) The frequency of the vibration can be tailored based on the patient's functional status (Semler et al, 2008).…”

Clinical Approaches of Whole-Body Vibration Exercises in Individuals with Stroke: A Narrative Revision

“…Moreover, as a mode of physical activity, WBVE has been identified as a feasible intervention with little to no adverse events [ 19 , 20 ]. WBVE has progressively been applied with beneficial outcomes to various clinical populations including stroke [ 7 , 21 ], obesity [ 22 ], rheumatoid arthritis [ 23 ], diabetes [ 24 ], spinal cord injury [ 25 ], chronic kidney disease [ 26 ], fibromyalgia [ 27 , 28 ], multiple sclerosis [ 29 ], cerebral palsy [ 30 , 31 ], Duchenne muscular dystrophy [ 32 ], osteogenesis imperfecta [ 33 ], osteoarthritis [ 34 ], and chronic obstructive pulmonary disease [ 35 ]. The effects of the WBVE may be due to neuromuscular responses to the interaction of the mechanical vibrations with the body and the tonic vibration response [ 36 – 39 ].…”