2024
DOI: 10.20944/preprints202402.1197.v1
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Whole Genome Alignment: Methods, Challenges, and Future Directions

Bacem Saada,
Siga Estevao,
Jing Zhang
et al.

Abstract: Whole genome alignment (WGA) is a critical process in comparative genomics, facilitating the detection of genetic variants and aiding our understanding of evolution. This paper offers a detailed overview and categorization of WGA techniques, encompassing suffix tree-based, anchors-based, and graph-based methods. It elaborates on the algorithmic properties of these tools, focusing on performance and methodological aspects. The paper underscores the latest progress in WGA, emphasizing the increasing capacity to … Show more

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