Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14

Ser, Hooi‐Leng; Tan, Loh Teng‐Hern; Tan, Wen-Si; Yin, Wai‐Fong; Chan, Kok-Gan

doi:10.36877/pmmb.a0000195

Cited by 14 publications

(13 citation statements)

References 69 publications

(74 reference statements)

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“…Certain unique strains thrive in extreme niches, such as the hypersaline bacteria and Streptomyces spp. isolated from mangrove soils are excellent sources of exogenous enzymes that work efficiently under extreme conditions [104,[400][401][402][403][404] . These extracellular enzymes supplemented by probiotics may function optimally at broader pH and salinity range, thereby extending the period of enzymatic digestion to facilitate more efficient hydrolysis of substrates [405,406] .…”

Section: Increasing the Digestive Enzyme Activitymentioning

confidence: 99%

Probiotics: Comprehensive Exploration of the Growth Promotion Mechanisms in Shrimps

Goh¹,

Tan²,

Law³

et al. 2023

Prog Micobes Mol Biol

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As feed accounts for a significant proportion of a farm’s expenditure, animal nutrition is one of the key profit determinants. Attributed to the size-dependent market value, enhancing shrimps' growth is essential to maximize profit. Despite not being the best option, antibiotics are often used as growth-promoting agents in farming. Although this trend is less explicit in aquaculture, increasing production yield is paramount, especially when intensive aquafarming compromises animal growth and increases disease prevalence. However, the environmental and clinical pitfalls of indiscriminate antibiotic usage are surfacing. Fortunately, increasing evidence demonstrated probiotics as a safer, more sustainable, and environmental-friendly substitute for antibiotics. Nonetheless, most studies are observational, and the growth-promotion mechanisms of these agents are yet to be elucidated. In this light, this review aims to decipher the growth promotion mechanisms of probiotics in shrimps based on the primary works conducted. Evidently, probiotic treatment modulates the gut microbiome composition. The growth promotion effect of probiotics is partly mediated through the production of bioactive compounds such as short-chain fatty acids, vitamins, and polyamines. Besides, elevated digestive enzyme activities following the introduction of probiotics may help enhance digestibility and utilization. Histological changes at the hepatopancreas and intestine were evident. Furthermore, probiotics may reinforce the protective mechanisms in the gut and strengthen immune function. Treated shrimps demonstrate better appetite and exhibit superior metabolic and growth-related genes profile. Contrasting these recognized mechanisms with antibiotics helps construct the initial framework for designing high-quality probiotics for growth enhancement in farmed animals.

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Section: Increasing the Digestive Enzyme Activitymentioning

confidence: 99%

Probiotics: Comprehensive Exploration of the Growth Promotion Mechanisms in Shrimps

Goh¹,

Tan²,

Law³

et al. 2023

Prog Micobes Mol Biol

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“…They are abundant in nature and have been frequently isolated from various sources such as soils, mangroves, and marine environments [76][77][78][79][80][81] . The use of streptomycetes as a probiotic has widely studied due to their ability to produce bioactive secondary metabolites during their life cycle [82][83][84][85][86][87][88] . Moreover, Streptomyces sp.…”

Section: Data Descriptionmentioning

confidence: 99%

Complete Whole Genome Sequence of Vibrio parahaemolyticus RP0132 Strain Isolated from Shrimp in Malaysia

Loo,

Tan,

Law

et al. 2023

Prog Micobes Mol Biol

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Vibrio parahaemolyticus is a Gram-negative, halophilic bacterium that is ubiquitous in marine environments. Its perilous co-existence with aquatic animals increases the risk of infections and diseases, especially those in aquaculture systems, thus resulting in reduced production and economic losses in the aquaculture industry. Moreover, V. parahaemolyticus can be easily transmitted to humans via consumption of contaminated seafood, resulting in gastroenteritis outbreaks. However, the rise in multidrug resistance within the species has challenged the efficacy of antimicrobial treatments against V. parahaemolyticus infections. Therefore, we report the genome sequence of V. parahaemolyticus RP0132 isolated from shrimp to gain insight into its antimicrobial resistance traits and potential resistance mechanisms. The findings will facilitate the development of effective anti-Vibrio agents to manage V. parahaemolyticus infections.

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“…In recent years, the uprising of various next-generation sequencing (NGS) platforms has revolutionized the field of natural product discovery, where the rapidly expanding microbial genomic and metagenomic datasets unravel a vast number of biosynthetic gene clusters that encode a lot more natural products than what has been characterized to date [48]. For instance, recent advances in genome mining have revealed that Streptomyces genomes contain numerous previously unknown cryptic biosynthetic clusters, suggesting that Streptomyces genomes remain a valuable resource for novel drug discovery [49,50]. Given that the unparallel contribution of Streptomyces bacteria to human health is a treasure trove of antibacterial agents [51], there is an increasing trend of studies that show renewed interest in the potential of Streptomyces bacteria in the production of antibiofilm compounds.…”

Section: Streptomyces Sp a Valuable Source For Anti-mrsa Biofilm Agentsmentioning

confidence: 99%

Streptomyces sp.—A Treasure Trove of Weapons to Combat Methicillin-Resistant Staphylococcus aureus Biofilm Associated with Biomedical Devices

Pusparajah

Letchumanan

Law

et al. 2021

IJMS

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Biofilms formed by methicillin-resistant S. aureus (MRSA) are among the most frequent causes of biomedical device-related infection, which are difficult to treat and are often persistent and recurrent. Thus, new and effective antibiofilm agents are urgently needed. In this article, we review the most relevant literature of the recent years reporting on promising anti-MRSA biofilm agents derived from the genus Streptomyces bacteria, and discuss the potential contribution of these newly reported antibiofilm compounds to the current strategies in preventing biofilm formation and eradicating pre-existing biofilms of the clinically important pathogen MRSA. Many efforts are evidenced to address biofilm-related infections, and some novel strategies have been developed and demonstrated encouraging results in preclinical studies. Nevertheless, more in vivo studies with appropriate biofilm models and well-designed multicenter clinical trials are needed to assess the prospects of these strategies.

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Whole-genome sequence of bioactive streptomycete derived from mangrove forest in Malaysia, Streptomyces sp. MUSC 14

Cited by 14 publications

References 69 publications

Probiotics: Comprehensive Exploration of the Growth Promotion Mechanisms in Shrimps

Probiotics: Comprehensive Exploration of the Growth Promotion Mechanisms in Shrimps

Complete Whole Genome Sequence of Vibrio parahaemolyticus RP0132 Strain Isolated from Shrimp in Malaysia

Streptomyces sp.—A Treasure Trove of Weapons to Combat Methicillin-Resistant Staphylococcus aureus Biofilm Associated with Biomedical Devices

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