Whole‐liver flip‐angle shimming at 7 T using parallel‐transmit k_T‐point pulses and Fourier phase‐encoded DREAMB1+ mapping

Abstract

PurposeTo obtain homogeneous signal throughout the human liver at 7 T. Flip angle (FA) shimming in 7T whole‐liver imaging was performed through parallel‐transmit kT‐point pulses based on subject‐specific multichannel absolute maps from Fourier phase‐encoded dual refocusing echo acquisition mode (PE‐DREAM).MethodsThe optimal number of Fourier phase‐encoding steps for PE‐DREAM mapping was determined for a 7T eight‐channel parallel‐transmission system. FA shimming experiments were performed in the liver of 7 healthy subjects with varying body mass index. In these subjects, first shimming and Fourier PE‐DREAM mapping were performed. Subsequently, three small‐flip‐angle 3D gradient‐echo scans were acquired, comparing a circularly polarized (CP) mode, a phase shim, and a kT‐point pulse. Resulting homogeneity was assessed and compared with estimated FA maps and distributions.ResultsFourier PE‐DREAM with 13 phase‐encoding steps resulted in a good tradeoff between accuracy and scan time. Lower coefficient of variation values (average [min‐max] across subjects) of the estimated FA in the volume of interest were observed using kT‐points (7.4 [6.6%–8.0%]), compared with phase shimming (18.8 [12.9%–23.4%], p < 0.001) and CP (43.2 [39.4%–47.1%], p < 0.001). kT‐points delivered whole‐liver images with the nominal FA and the highest degree of homogeneity. CP and phase shimming resulted in either inaccurate or imprecise FA distributions. Here, locations having suboptimal FA in the estimated FA maps corresponded to liver areas suffering from inconsistent signal intensity and T1‐weighting in the gradient‐echo scans.ConclusionHomogeneous whole‐liver 3D gradient‐echo acquisitions at 7 T can be obtained with eight‐channel kT‐point pulses calculated based on subject‐specific multichannel absolute Fourier PE‐DREAM maps.

Tailored and universal parallel transmit broadband pulses for homogeneous 3D excitation of the human heart at 7T

“…Furthermore, multiple sources of motion, including respiration, cardiac activity, and blood flow, exacerbate the technical challenges encountered in UHF MRI when targeting areas within the human body, such as the heart or liver. [9][10][11][12][13][14] A range of innovative solutions has been proposed to address these challenges, encompassing the integration of multi-transmit RF coils and parallel transmission (pTx) techniques [15][16][17][18][19][20][21] using volunteer-specific B + 1 information alongside motion-robust non-Cartesian acquisition schemes and advanced reconstruction approaches. 11,22,23 Dynamic pTx employs, in contrast to static pTx, temporally changing RF and gradient waveforms.…”

“…Although various approaches have been developed to address the inhomogeneous transmit field, 2,6–8 the application of UHF MRI to the human body, which is usually larger in size than the human brain, requires specialized methodologies to tackle this issue effectively. Furthermore, multiple sources of motion, including respiration, cardiac activity, and blood flow, exacerbate the technical challenges encountered in UHF MRI when targeting areas within the human body, such as the heart or liver 9–14 …”