Why aortic elasticity differs among classical and non-classical mitral valve prolapsed?

Abstract

We concluded that the elastic properties of the aorta is increased in patients with classic MVP. Further large scale studies should be performed to understand of morphological and physiological properties of the aorta in patients with MVP.

Aortic elastic properties do not differ in patients with mitral valve prolapse

“…Previously, Unlu M. et al investigated elastic properties of the aorta in young male patients with classical and non-classical MVP and found that aortic strain and aortic distensibility were increased whereas the aortic stiffness index was decreased in the classical MVP group. 4 Similarly, aortic stiffness index was found to be lower and aortic distensibility to be higher in patients with MVP in another study. 5 Considering that the elasticity of the valvular tissue is increased in mitral valve prolapse, the existence of a concomitant reduction in the stiffness of aorta as revealed in these studies was an expected finding.…”

“…Several studies on this topic revealed conflicting results. [4][5][6] Herein, we also aimed to investigate the elastic properties of the aorta in patients with MVP.…”

Aortic elasticity and carotid intima-media thickness in children with mitral valve prolapse

“…There is only one adult study comparing elasticity parameters of aorta between classical and non-classical mitral valve prolapse; it found reduced aortic stiffness in the ascending aorta in classical mitral valve prolapse patients than in non-classical mitral valve prolapse patients. 41 Autonomic functions may affect aortic distensibility and stiffness. 42 Excessive vagal tone and alfa-adrenergic hyperactivity was found in mitral valve prolapse patients.…”

“…Physical examination findings, weight and height measurements, and blood pressures of all patients were recorded. Patients were divided into two groups according to the leaflet thickness (classical and non-classical mitral valve prolapse) because a previous adult study has shown increased aortic distensibility and decreased stiffness in classical form of mitral valve prolapse 14 . Patients were also divided into groups (younger versus older) according to age (6–12 years versus 13–20 years) because aortic stiffness increases with age in the normal population 15 .…”

“…Patients were divided into two groups according to the leaflet thickness (classical and non-classical mitral valve prolapse) because a previous adult study has shown increased aortic distensibility and decreased stiffness in classical form of mitral valve prolapse. 14 Patients were also divided into groups (younger versus older) according to age (6-12 years versus 13-20 years) because aortic stiffness increases with age in the normal population. 15 The control group was also divided into two groups according to age and comparisons between the study and control groups were carried out between corresponding age groups.…”