Why confine chorionic villus biopsy to single pregnancies?

The rising rate of multiple pregnancies and its association with advanced maternal age has expanded the need for prenatal diagnosis in twins and higher order gestations. The complexity of the invasive diagnostic procedures and the risk of loss of an unaffected twin raise significant clinical, technical and ethical issues. In this review we discuss the specific issues of early scanning, counseling and determination of chorionicity prior to invasive procedures in twins. We present the available data describing the risk associated with these procedures in twins and compare data of fetal loss rate from different studies. We also discuss the issues of fetal blood sampling and late karyotyping in twin pregnancies.

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Invasive diagnostic procedures in twin pregnancies

Weisz

Rodeck

2005

Prenatal Diagnosis

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Spezielle Aspekte der nicht-invasiven und invasiven Pränataldiagnostik bei Mehrlingen

et al. 1998

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Chorionic villus sampling in multiple pregnancies

Appelman

Vinkler

Caspi

1999

European Journal of Obstetrics & Gynecology and Reproductiv

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Why confine chorionic villus biopsy to single pregnancies?

Cited by 4 publications

References 10 publications

Invasive diagnostic procedures in twin pregnancies

Invasive diagnostic procedures in twin pregnancies

Spezielle Aspekte der nicht-invasiven und invasiven Pränataldiagnostik bei Mehrlingen

Chorionic villus sampling in multiple pregnancies

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