A forward trunk lean sometimes occurs to compensate for quadriceps muscle weakness. Since muscle weakness in the lower extremities is commonly observed in the elderly, quadriceps weakness may trigger age-related postural change. The objective of this study was to ascertain the association between forward trunk lean during walking and musculoskeletal strength in females aged between 46 and 79 years. Musculoskeletal functions (range of joint motion, degree of kyphosis, muscle strength) and joint moments during walking were measured for 13 females. Subjects who showed greater joint moments during walking tended to lean more. Moderate association was seen between mean trunk angle during walking and knee extension moment (r = 0.535, p = 0.060). There was no statistically significant correlation between the strength of the quadriceps muscle and the mean trunk angle in walking subjects (r = 0.095, p = 0.758). These observations suggested that muscle weakness in the quadriceps is largely independent of leaning of the trunk for this sample of subjects. Other factors may change the posture to a stoop, such as severe thoracic kyphosis, poor balance control, or fear of falling.