We posit that the high rates of suicidal behavior by teenage Hispanic females reported in large-scale surveys can be understood as a cultural phenomenon, a product of specific elements of the history, tradition, ideology, or social norms of a particular society, and that treatment interventions must take family and cultural factors into consideration. For over a decade, surveys have reported that among ethnic and racial minority youth in the United States, Latinas have the highest rates of suicidal behavior compared to African American and non-Hispanic White adolescent females. However, other research shows that the psychological profiles of suicidal Latina adolescent girls and the risk factors for Latina suicidal behavior may not be that different from non-Hispanic suicidal adolescent females. The unique situation of adolescent Latinas involves the convergence of cultural and familial factors (i.e., familism, acculturation, relatedness, autonomy, etc.) with the developmental, social, and individual factors frequently associated with suicidal behaviors. Based on this background, familyoriented interventions appear to be the most appropriate approach to the prevention and treatment of Hispanic suicidal girls. Factors implicated in Latina suicidal behavior and community-based interventions that include the adolescent and her family are suggested. Although data do not distinguish Latino youth by country of origin or heritage, Latino 1 youth of both sexes have shown consistently higher rates of suicidal ideation, plans, and behavior than their non-Hispanic counterparts, except for the category of youth designated as "Other" (which includes Native American youth). In spite of the higher than average reports of suicidal behavior among Hispanic youth, their actual rates of suicides are lower than those of non-Hispanic White and Native American adolescents, but higher than those of nonHispanic Black youth.Although these reports confirm observations from other epidemiological and clinical research as well as observations made by many urban mental health clinicians working with Latino populations, empirical literature explaining this dramatic difference is quite sparse. With our current state of knowledge, we are not yet able to explain, with a high degree of empirical certainty, what the reasons are that explain why the rates of suicidal ideation and attempts are higher among Latino youth. In this article, we do not purport to present explanations derived from rigorous, first-hand empirical research. Rather, we integrate knowledge from past