Why Give My Surgical Patients Probiotics

Kotzampassi, Katerina

doi:10.3390/nu14204389

Cited by 7 publications

(6 citation statements)

References 62 publications

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“…The potential beneficial effect of probiotics in the prevention of anastomotic leaks is currently being investigated (NCT05164887) [ 76 ]. For example, it was shown that intestinal dysbiosis in the form of low diversity and virulence shift of Enterobacteriaceae, Pseudomonas aeruginosa, and Enterococcus faecalis plays an important role in the pathophysiology of anastomotic leaks [ 25 , 77 ].…”

Section: Resultsmentioning

confidence: 99%

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The Role of Probiotics in Inflammation Associated with Major Surgery: A Narrative Review

et al. 2023

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Background: Gut microbiota is well-known for its ability to maintain intestinal homeostasis. However, the disruption of this homeostasis, known as dysbiosis, leads to multiple consequences, including local and systemic inflammation. Surgery-induced inflammation is a major concern for patients, as it leads to many infectious and non-infectious complications. Objective: The purpose of this review was to explore the role of probiotics and symbiotics in surgery-induced inflammation and to determine if their use is effective in combatting inflammation and its complications Methods and Materials: A literature search was conducted, and articles published only in English, until December 2022 were included. The results are reported in the form of a narrative review. Results: The perioperative use of probiotics and/or symbiotics results in lower risk of infectious complications, including reduced rates of surgical site infections, respiratory and urinary tract infections, shorter hospital stays, and fewer days of antibiotic administration. It also contributes to reducing non-infectious complications, as it mitigates systemic and local inflammation via maintenance of the intestinal barrier, improves intestinal mobility, and is associated with lower rates of postoperative pain and anastomotic leak. Conclusions: Restoring gut microbiota after disruptions caused by surgery may accelerate local healing processes, attenuate systemic inflammation, and may thus prove beneficial to certain populations.

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Section: Resultsmentioning

confidence: 99%

“…It is possible that probiotics may help relieve postoperative pain [ 77 ]. Rousseaux et al found that oral administration of Lactobacillus spp.…”

Section: Resultsmentioning

confidence: 99%

The Role of Probiotics in Inflammation Associated with Major Surgery: A Narrative Review

et al. 2023

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“…On the other hand, it has been documented that the administration of heterogenous but not single-strain probiotics, could significantly reduce surgery related complications, as well as surgical and non-surgical site infections [ 194 ]. These effects are however irregular with large variation in outcomes due to the non-homogeneity in probiotic types, amount, and frequency of administration across studies [ 194 , 195 ]. This predicament is further compounded by inherent microbiome differences across individuals [ 190 ].…”

Section: Discussionmentioning

confidence: 99%

Accounting for the health risk of probiotics

Liu,

Zhao,

Wong

2024

Heliyon

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“…Along with increasing evidence of the remarkable effects of probiotics described in several clinical trials, numerous studies summarized the usefulness of oral probiotic supplementation. This approach is gaining attention as a new therapeutic strategy for its ability to promote the healing process by preventing postoperative or surgical site infections, increasing colonic and gut motility, and alleviating postoperative complications [ 73 ]. A clinical controlled, randomized trial performed on 103 patients with multiple trauma who required surgical intervention revealed that the incidence of surgical site infections could be reduced through the oral administration of a combination of probiotics, including Lactiplantibacillus plantarum UBLP-40, L. acidophilus LA-5, S. boulardii Unique-28, and Bifidobacterium animalis subsp.…”

Section: Human Studies Supporting the Role Of Probiotics In Wound Hea...mentioning

confidence: 99%

Probiotics in Wound Healing

Bădăluță,

Curuțiu,

Dițu

et al. 2024

IJMS

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Wound infections caused by opportunistic bacteria promote persistent infection and represent the main cause of delayed healing. Probiotics are acknowledged for their beneficial effects on the human body and could be utilized in the management of various diseases. They also possess the capacity to accelerate wound healing, due to their remarkable anti-pathogenic, antibiofilm, and immunomodulatory effects. Oral and topical probiotic formulations have shown promising openings in the field of dermatology, and there are various in vitro and in vivo models focusing on their healing mechanisms. Wound dressings embedded with prebiotics and probiotics are now prime candidates for designing wound healing therapeutic approaches to combat infections and to promote the healing process. The aim of this review is to conduct an extensive scientific literature review regarding the efficacy of oral and topical probiotics in wound management, as well as the potential of wound dressing embedding pre- and probiotics in stimulating the wound healing process.

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Why Give My Surgical Patients Probiotics

Cited by 7 publications

References 62 publications

The Role of Probiotics in Inflammation Associated with Major Surgery: A Narrative Review

The Role of Probiotics in Inflammation Associated with Major Surgery: A Narrative Review

Accounting for the health risk of probiotics

Probiotics in Wound Healing

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